Prof. L.V. Zhuravlyova, PhD N.V. Sokolnikova, PhD T.A. Rogachova Kharkiv National Medical University The purpose of this review article is to analyze current information on the molecular mechanisms of gestational diabetes and the prospects for their use in the further development of new effective treatments for this common pathology. Decreased ability of insulin to bind…
Diabetes mellitus, metabolic syndrome
Clinical and pathogenetic rationale for the prevention and treatment of obesity.
Prof. O.M. Korzh. Kharkiv Medical Academy of Postgraduate Education. Numerous studies in recent years have identified obesity as a key cause of the development of type 2 diabetes, metabolic syndrome and cardiovascular diseases, which are among the most significant public health problems in most countries of the world. The high prevalence of obesity, which determines…
The role of dipeptidylpeptidase-4 inhibitors in the current therapy of type 2 diabetes mellitus.
Prof. L.V. Zhuravlyova, M.V. Filonenko. Kharkiv National Medical University. Recent advances in the study of the pathogenesis of type 2 diabetes, including the mechanisms of regulation of postprandial blood glucose level, have led to the emergence of new treatment strategies aimed at overcoming dysfunction of the Langerhans islands, including those that affect the incretine hormones…
Biomarker of systemic inflammation in women with arterial hypertension and obesity, depending on the presence of type 2 diabetes.
PHD N.M. Kyrychenko Sumy State University Type 2 diabetes mellitus and related complications are serious global public health problem. The presence of chronic systemic inflammation associated with an increase body weight and changes in the functions and activity of adipose tissue can cause the development of disorders in the regulation of glucose metabolism and in…
Heart failure in patients with diabetic cardiomyopathy: modern methods of treatment
Prof. L.V. Zhuravlyova, N.V. Sokolnikova, T.A. Rogachova Kharkiv National Medical University Currently, all over the world, type 2 diabetes mellitus and the heart failure are developing into an epidemic. For the first time, diabetic cardiomyopathy as an independent diagnostic unit was described in 1972 by Shirley Rubler and colleagues. Currently, the most common phenotype of…
Heart failure in patients with diabetic cardiomyopathy: features of pathogenesis and diagnosis
Prof. L.V. Zhuravlyova, as. prof. T.A. Rogachova, as. prof. N.V. Sokolnikova. Kharkiv National Medical University Currently, all over the world, type 2 diabetes mellitus and the heart failure are developing into an epidemic. In 1972, Shirley Rubler and colleagues defined cardiomyopathy, which was independent of atherosclerosis and hypertension, as diabetic cardiomyopathy. Recently, the so-called restrictive type…
Cardiovascular complications in diabetes mellitus: the role of hyperglycemia
Prof. O.M. Korzh. Kharkiv Medical Academy of Postgraduate Education. The article discusses the relationship of glycemia control with the development of mid-vascular pathology. Proved a clear link glycemic control with a reduced risk of micro- and macrovascular complications of diabetes. At present, the ideology of early intervention is actively developing and is gaining more and…
Patient with hyperchlicemia at the family doctor
PhD Pasiieshvili T.M., Koryak V.V.* Kharkiv National Medical University.Department of General Practice — Family Medicine and Internal Diseases. *Educational and scientific medical complex «University Clinic» of KhNMU Issues of prevalence, preconditions for the course of diabetes mellitus are considered in the paper. The role of insulin in the body is determined. Nosologies in which hyperglycemia…
Features of insulin therapy in patients with type 1 diabetes mellitus during pregnancy
Prof. Zhuravlyova LV, Rogachova TA Kharkiv National Medical University. Until recently, pregnancy in type 1 diabetes mellitus caused high risk of complications for the mother and severe congenital abnormalities for the child. The main problems of pregnant women with diabetes were difficulties in achieving stable normal blood glucose level, avoiding hypoglycemia and ketoacidosis. Control of DM-1…
Prospects for the rehabilitation of patients with type 2 diabetes mellitus
Prof. O. N. Beletskaya Kharkiv medical academy of postgraduate education The perspectives of treatment of patients with type 2 diabetes mellitus in the paradigm of physical and rehabilitation medicine are considered. The concept of pathogenesis of type 2 diabetes is proposed, as a consequence of the age and constitutional predisposition to disadaptation of the organism…