Pathogenetic features of the combined course of arterial hypertension and diabetes mellitus 2 type

Prof. Bilovol O.M., prof. Bobronnikova L.R., Al-Trawneh O.V. Kharkiv National Medical University.

In the article features of pathogenetic mechanisms of the combined course of arterial hypertension and type2 diabetes mellitus are considered. This pathology potentiates the development of micro- and macrovascularcomplications, raises cardiovascular risk. Concomitant abdominal obesity contributes to the imbalance ofadipocytokines, and complicates the course of type 2 diabetes. It was established that polymorphism of candidategenes associated with the development and progression of insulin resistance, which is of interest for further study.

Key Words: arterial hypertension, diabetes mellitus type 2, pathogenesis mechanisms of development, adipokines imbalance, gene polymorphism.

Belovol AN, Bobronnikova LR, Al’-Trawneh OV. [Pathogenetic features of the combined course of arterial hypertension and diabetes mellitus 2 type]. Shidnoevr. z. vnutr. simejnoi med. 2017;1:4-9. Russian.


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