Prof. O.M. Korzh, assoc. prof. B.A. Rogozhin Kharkiv National Medical University This article presents a systematic study of the development of medical technologies used in the diagnosis, treatment, and prevention of arterial hypertension (AH) from the 17th century to the 1940s. It examines the evolution of blood pressure (BP) measurement techniques and their clinical application….
Cardiology
Metabolic effects of vitamin D
Assoc. prof. I.P. Dunaieva, assoc. prof. O.L. Yakovenko, prof. N.O. Kravchun Kharkiv National Medical University The article is devoted to the analysis of the metabolic effects of vitamin D, its role in the prevention and treatment of diseases. The metabolism of vitamin D, the mechanisms of influence on various body systems, as well as the…
Arterial hypertension in obese patients: clinical and pathogenetic features
Prof. O.M. Korzh, prof. L.V. Cherkashyna, assoc. prof. L.M. Tsogoeva Kharkiv National Medical University Induced arterial hypertension (AH) is one of the forms of AH, the pathogenetic mechanisms of which are well studied: the main reason is the disruption of the functioning of visceral adipose tissue, which leads to activation of the renin-angiotensin-aldosterone system, imbalance…
To the problem of optimal antihypertensive therapy for patients with arterial hypertension and type 2 diabetes (according to the 2023 European Society of Hypertension Recommendations)
Ph.D. D.K. Miloslavsky, prof. S.M. Koval Government Institution «L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine», Kharkiv The review of the problem of optimal antihypertensive therapy for patients with arterial hypertension (AH) with type 2 diabetes mellitus (T2DM) through the prism of the 2023 European Society of Hypertension Guidelines…
Effect of revascularization of coronary arteries on mechanical dyssynchrony of left ventricular myocardium in patients with coronary heart disease
Asp. Fatma Mehtieva1, prof. O.V. Bilchenko2 1 V.N. Karazin Kharkiv National University. Department of Internal Medicine. 2 Kharkiv National Medical University. Department of therapy №1 Introduction. Defining a treatment strategy for patients with stable coronary heart disease will require the development of personalized criteria, among which the assessment of myocardial dyssynchrony is considered promising. The…
Relationships between home blood pressure monitoring parameters and plasma catestatin and relaxin-2 levels in patients with essential hypertension and type 2 diabetes mellitus
Pankova O.A., prof. Korzh O.M. Kharkiv National Medical University Objective. To investigate the peculiarities of home blood pressure monitoring parameters in patients with essential hypertension (EH) in combination with type 2 diabetes mellitus (T2DM) and to evaluate their relationships with plasma catestatin (CTS) and relaxin-2 (RLN-2) levels. Materials and methods. 106 patients with EH, 55…
Features of arterial hypertension in obesity
Prof. Korzh O.M. Kharkiv National Medical University Hypertension in obesity is a fairly common problem, and it has its own characteristics. Obesity promotes inflammation in the body, which can damage blood vessels and lead to atherosclerosis, which also contributes to increased blood pressure. Obesity can lead to increased resistance to blood flow in vessels through…
Сlinic and pathogenic significance of omentin
Prof. Korzh O.M., asst. Fylenko Y.M. Kharkiv National Medical University Today, adipokines are important cellular signaling proteins synthesized by adipose tissue and involved in a variety of processes, including inflammation, lipid and glucose metabolism, insulin sensitivity, endothelial cell function, angiogenesis, blood pressure regulation, and many others. This review examines the immunological and endocrine function of…
Chronic heart failure and osteoporosis: etiological and clinicalpathogenetic relationships
Prof. Korzh O.M., PHD Korzh I.V. Kharkiv National Medical University Sytenko Institute of Spine and Joint Pathology of National Academy of Medical Sciences of Ukraine Current epidemiological and clinical data confirm the relationship between chronic heart failure (CHF) and osteoporosis (OP), which cannot be explained only by aging and the use of pharmacological drugs. Clinical…
Comorbid patient: an interdisciplinary problem (literature review)
Prof. Kravchun N.O., assoc. prof. Dunaieva I.P., assoc. prof. Yakovenko O.L., prof. Kravchun P.P. Kharkiv National Medical University The comorbidity of arterial hypertension (AH), type 2 diabetes mellitus (T2DM), obesity leads to the early development of atherosclerotic lesions of coronary and cerebral vessels, which, in turn, significantly accelerates the occurrence of coronary arterial disease (CHD),…
Contemporary antianginal pharmacotherapy: choosing the optimal solution to the problem
Prof. Korzh О.М. Kharkiv National Medical University The formation of antianginal pharmacotherapy has gone a long way, characterized by the search for the main factors of effective pharmacodynamics. The article presents an analysis of the use of drugs with different pharmacological properties in patients suffering from angina pectoris in a historical aspect, shows the evolution…
Insulin resistance and cardiovascular diseases: focus on common in pathogenesis and treatment
Prof. Zhuravlyova L.V., asst. Rohachova T.A., assoc. prof. Sokolnikova N.V., assoc. prof. Yankevich O.O. Kharkiv National Medical University Department of Internal Medicine №3 and Endocrinology The prevalence of cardiovascular disease and type 2 diabetes has increased dramatically worldwide over the past 30 years. These diseases have become a worldwide epidemic and the main cause of…
The personalized approach to the prevention of cardiovascular diseases
Prof. Korzh O.M. Kharkiv National Medical University The article presents a number of major updates on the assessment of the risk of cardiovascular complications and the principles of preventive intervention based on the materials of the analyzed clinical recommendations. Previous European guidelines focused on risk stratification and prevention of risk factors, whereas the updated European…
The contribution of some biologically active substances of adipose tissue to the development of cardiovascular complications in comorbid patients
Prof. Kravchun P.P., Assoc.prof. Yakovenko O.L., Assoc.prof. Dunaieva I.P., prof. Kravchun N.O. Kharkiv National Medical University The contribution of some biologically active substances of adipose tissue to the development of cardiovascular complications in comorbid patients. Adipose tissue hormones — adipokines — vaspin and omentin, which control homeostasis, lipid and glucose metabolism, have attracted scientific interest…
Evolution of approaches to the treatment of acute coronary syndromes: from Eisenhower’s heart attack to modern approaches to treatment
Prof. Korzh O.M. Kharkiv Medical Academy of Postgraduate Education US President Dwight Eisenhower suffered an acute myocardial infarction in 1955. But in Eisenhower’s case, the beginning was unusual. Furthermore, ECGs were not widely available, cardiac enzymes were not used as diagnostic tests, and echocardiography or coronary angiography were not available to emergency physicians or cardiologists….
Diabetic dyslipidemia: focus on pathogenesis and treatment
Prof. Zhuravlyova L.V., PHD Sokolnikova N.V., PHD Rogachova T.A. Kharkiv National Medical University Atherosclerotic cardiovascular diseases are the most common cause of death in the developed countries of the world. Patients with diabetes mellitus 2 type are 2-4 times more likely to die from these diseases compared to patients without diabetes. This review discusses the…
The potential of catestatin in the diagnostics of cardiovascular diseases: current data and perspectives
Pankova O. Kharkiv medical academy of postgraduation education Cardiovascular diseases are not only the most common non-communicable diseases, but also occupy the leading place in the structure of total mortality in the world population. Among the wide range of pathogenetic mechanisms of the above-mentioned pathology, an increase in the activity of the sympathetic nervous system…
Cardiomyopathy. Clinic. Diagnostics. Treatment
Assoc. prof. Dvyashkina Yu.I., assoc. prof. Khomenko L. O., Oparina T.N. Kharkiv Medical Academy of Postgraduate Education The article provides modern information about cardiomyopathy: classification, features of the clinical picture, diagnosis depending on the form of cardiomyopathy. Particular attention is paid to the treatment and prevention of this pathology. Key Words: dilated cardiomyopathy, hypertrophic cardiomyopathy,…
Modern concepts on the pathogenesis and treatment of chronic heart failure: focus on the metabolic syndrome and its consequences
Prof. L.V. Zhuravlyova, PHD N.V. Sokolnikova, PHD T.A. Rogachova Kharkiv national medical university In recent decades, there has been a steady increase in the prevalence of chronic heart failure worldwide, which is estimated to affect up to 2% of the adult population and up to 10% of the elderly. The pathogenesis of chronic heart failure…
Modern approaches to the treatment of atrial firillation in patients with diabetes mellitus
S.A. Serik, V.I. Strona National Institute of Therapy L.T. Malaya NAMS of Ukraine, Kharkiv, Ukraine The article analyzes the main clinical and theoretical data on the features of the treatment of atrial fibrillation (AF) in combination with diabetes mellitus (DM). Differentiated approaches to the correction of these cardiac arrhythmias in this category of patients are…