Prof. O.M. Korzh, prof. L.V. Cherkashyna, assoc. prof. L.M. Tsogoeva Kharkiv National Medical University, Department of general practice-family medic Prediabetes is a common metabolic condition that often remains undiagnosed and significantly increases the risk of developing type 2 diabetes and cardiovascular complications. This article examines the role of the family physician in the early detection…
Diabetes mellitus, metabolic syndrome
Features of motor-secretory disorders and distribution of fat tissue in patients with gastroesophageal reflux disease with common obesity
Prof. O.A. Oparin, assoc. prof. Yu.G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. A.E. Novokhatnya, assist. O.M. Kashirttseva Kharkiv National Medical University Ukrainian Humanitarian Institute It has been established that patients with GERD with concomitant obesity have secretory disorders, and in patients with isolated GERD, increased gastric juice aggression comes to the fore, and in…
Features of the etiology and clinical course of nosocomial infections in diabetes (literature review)
Assoc. prof. I.I. Medvid, prof. L.S. Babinets, assoc. prof. I.I. Herasymets I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine Relevance. Diabetes mellitus affects approximately 12 % of the adult population and is a serious burden on the health care system. It affects about 463 million people worldwide. Patients with diabetes…
Therapeutic effect of peppermint oil application in patients with irritable bowel syndrome and metabolic syndrome
Prof. O.I. Sergienko, assoc. prof. A.I. Сhernobai, assoc. prof. A.Y. Novokhatnia, assoc. prof. A.V. Vlasenko, assoc. prof. Y.K. Sikalo Kharkiv National Medical University Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, affecting almost 20% of the population, causing significant functional and socioeconomic burden. An existing association between functional bowel disorders,…
Metabolic effects of vitamin D
Assoc. prof. I.P. Dunaieva, assoc. prof. O.L. Yakovenko, prof. N.O. Kravchun Kharkiv National Medical University The article is devoted to the analysis of the metabolic effects of vitamin D, its role in the prevention and treatment of diseases. The metabolism of vitamin D, the mechanisms of influence on various body systems, as well as the…
Analysis of the relationship between the parameters of the autonomic nervous system and the clinical course of type 2 diabetes mellitus in combination with chronic pancreatitis
Prof. L. S. Babinets, asp. O. V. Redkva I.Ya. Horbachevsky Ternopil National Medical University Ministry of Health of Ukraine Abstract. Currently, the possible relationship between the function of the autonomic nervous system (ANS) and type 2 diabetes mellitus (T2DM) is being actively studied. ANS imbalance is also mentioned by researchers as one of the possible…
To the problem of optimal antihypertensive therapy for patients with arterial hypertension and type 2 diabetes (according to the 2023 European Society of Hypertension Recommendations)
Ph.D. D.K. Miloslavsky, prof. S.M. Koval Government Institution «L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine», Kharkiv The review of the problem of optimal antihypertensive therapy for patients with arterial hypertension (AH) with type 2 diabetes mellitus (T2DM) through the prism of the 2023 European Society of Hypertension Guidelines…
Features of lipid and carbohydrate metabolism in patients with gastroesophageal reflux disease against type 2 diabetes, depending on the presence of obesity
Bondar-Кeleberda O.S. Kharkiv National Medical University The aim: To reveal the peculiarities of lipid and carbohydrate metabolism in patients with isolated gastroesophageal reflex disease (GERD), GERD on the background of type 2 diabetes mellitus (T2DM) and with type 2 DM, depending on the body mass index (BMI). Materials and methods. To participate in the study,…
Relationships between home blood pressure monitoring parameters and plasma catestatin and relaxin-2 levels in patients with essential hypertension and type 2 diabetes mellitus
Pankova O.A., prof. Korzh O.M. Kharkiv National Medical University Objective. To investigate the peculiarities of home blood pressure monitoring parameters in patients with essential hypertension (EH) in combination with type 2 diabetes mellitus (T2DM) and to evaluate their relationships with plasma catestatin (CTS) and relaxin-2 (RLN-2) levels. Materials and methods. 106 patients with EH, 55…
Сlinic and pathogenic significance of omentin
Prof. Korzh O.M., asst. Fylenko Y.M. Kharkiv National Medical University Today, adipokines are important cellular signaling proteins synthesized by adipose tissue and involved in a variety of processes, including inflammation, lipid and glucose metabolism, insulin sensitivity, endothelial cell function, angiogenesis, blood pressure regulation, and many others. This review examines the immunological and endocrine function of…
Comorbid patient: an interdisciplinary problem (literature review)
Prof. Kravchun N.O., assoc. prof. Dunaieva I.P., assoc. prof. Yakovenko O.L., prof. Kravchun P.P. Kharkiv National Medical University The comorbidity of arterial hypertension (AH), type 2 diabetes mellitus (T2DM), obesity leads to the early development of atherosclerotic lesions of coronary and cerebral vessels, which, in turn, significantly accelerates the occurrence of coronary arterial disease (CHD),…
Insulin resistance and cardiovascular diseases: focus on common in pathogenesis and treatment
Prof. Zhuravlyova L.V., asst. Rohachova T.A., assoc. prof. Sokolnikova N.V., assoc. prof. Yankevich O.O. Kharkiv National Medical University Department of Internal Medicine №3 and Endocrinology The prevalence of cardiovascular disease and type 2 diabetes has increased dramatically worldwide over the past 30 years. These diseases have become a worldwide epidemic and the main cause of…
Endotoxicosis and inflammation as predictors of the deepening of panсreatic functional insufficiency in chronic pancreatitis in combination with type 2 diabetes
Prof. Babinets L.S., asp. Zemlyak O.S., doctorant Halabitska I.M. I.Horbachevsky Ternopil National Medical University According to scientists, a significant role in the progression of chronic pancreatitis (CP) and diabetes mellitus (DM), as well as in the occurrence of complications of these diseases, is played by inflammation and endogenous intoxication by the products of protein breakdown…
Modern concepts on the pathogenesis and treatment of chronic heart failure: focus on the metabolic syndrome and its consequences
Prof. L.V. Zhuravlyova, PHD N.V. Sokolnikova, PHD T.A. Rogachova Kharkiv national medical university In recent decades, there has been a steady increase in the prevalence of chronic heart failure worldwide, which is estimated to affect up to 2% of the adult population and up to 10% of the elderly. The pathogenesis of chronic heart failure…
Modern approaches to the treatment of atrial firillation in patients with diabetes mellitus
S.A. Serik, V.I. Strona National Institute of Therapy L.T. Malaya NAMS of Ukraine, Kharkiv, Ukraine The article analyzes the main clinical and theoretical data on the features of the treatment of atrial fibrillation (AF) in combination with diabetes mellitus (DM). Differentiated approaches to the correction of these cardiac arrhythmias in this category of patients are…
Atrial fibrillation in diabetic patients.
Prof. S.A. Serik, PHD V.I. Strona National Institute of Therapy. L.T. Malaya NAMS of Ukraine, Kharkiv The article summarizes the main clinical and theoretical data on features of atrial fibrillation (AF) course in combination with diabetes mellitus (DM). The potential relationship between these comorbid conditions is analyzed on the basis of the results of epidemiological…
The relationship between diabetes mellitus and heart rhythm disorders: a focus on common pathophysiological mechanisms and modern treatment strategies.
Prof. Zhuravlyova L.V., PHD Sokolnikova N.V., PHD Rogachova T.A. Kharkiv National Medical University The aim of this review article is the analysis the latest evidence based scientific data on the pathophysiological association between diabetes mellitus and heart arrhythmias and the most acceptable treatment possibilities for their correction. In recent decades, the worldwide prevalence of diabetes…
Optimization of the diagnosis of preclinical renal dysfunction in arterial hypertension and its combination with type 2 diabetes mellitus.
Hajibabirova Lala Mehman Scientific Research Institute of Cardiology named after J. Abdullayev, Baku. In order to optimize the diagnosis of early renal dysfunction in patients with arterial hypertension and its combination with type 2 diabetes mellitus, we examined 100 patients aged 35 to 58 years (mean age 46.8 ± 0.68). The first group included 50…
The importance of vaspin in external and internal secretory activity of the pancreas.
D. Pylov Kharkiv National Medical University, Department of Internal Medicine №3 and Endocrinology To analyze the data of the scientific literature on the importance of vaspin as a pathogenetic link in the development of insufficiency of exocrine function of the pancreas in type 2 diabetes patients in combination with chronic pancreatitis and. Literary sources were searched…
Levels of fibroblast growth factor and sulfated glycosoaminoglycans in connective tissue metabolism in patients with mitral valve prolapse and type 1 diabetes mellitus.
O.Ye. Nikolenko, S.B. Pavlov*, O.M. Korzh* V.N.Karazin Kharkiv National University, Ukraine. *Kharkiv Medical Academy of Postgraduate Education, Ukraine In order to study the influence of the main fibroblast growth factor on the indicators of the state of the main substance of the extracellular matrix, a comparative analysis of their levels in the blood serum was…