Atrial fibrillation in diabetic patients.[:]

Prof. S.A. Serik, PHD V.I. Strona

National Institute of Therapy. L.T. Malaya NAMS of Ukraine, Kharkiv

The article summarizes the main clinical and theoretical data on features of atrial fibrillation (AF) course in combination with diabetes mellitus (DM). The potential relationship between these comorbid conditions is analyzed on the basis of the results of epidemiological and randomized studies, the gender features of the course of AF in this category of patients are assessed. Particular attention is paid to pathogenetic bases of AF development in DM (fibrosis, neurohumoral regulation, impaired energy metabolism of cardiomyocytes, oxidative stress, genetic factors, electrolyte metabolism disorders).

Key Words: diabetes mellitus, atrial fibrillation, risk factors, atrial fibrosis, autonomic regulation, connexin.

https://dx.doi.org/10.15407/internalmed2021.02.103

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