Prof. O.I. Sergienko, assoc.prof. A.I. Chernobai, asp. G.Yu. Tegelska, assос.prof. A.I. Novokhatnya, assос.prof. Yu.K. Sikalo Kharkiv National Medical University, Department of therapy, gastroenterology and dieteti The article presents a modern description of the phenotypes of diverticular disease. The risk factors of diverticular disease, the features of the course of the disease and the ethical role of…
Gastroenterology
Diagnostic accuracy of shear wave elastography for staging liver fibrosis in diabetic patients with NAFLD
V.N. Najafova Azerbaijan Medical University, Department of Radiation Diagnostics and Therapy Aim. To assess the diagnostic accuracy of shear wave elastography for staging liver fibrosis in patients with diabetes mellitus and non-alcoholic fatty liver disease. Results. Our study demonstrates an increase in liver stiffness in diabetic patients with hepatic steatosis (p < 0.05) . In…
Psychosomatic and vegetative state in patients with gastroesophageal reflux disease with concomitant obesity
Prof. A.G. Oparin, PHD Y.G. Fedchenko, PHD A.V. Blagoveshchenska, PHD A.E. Novokhatnya, PHD O.M. Kashirtseva, PHD I.P. Korenovsky, PHD L.O. Khomenko Kharkiv National Medical University, Ukrainian Humanitarian Institute The paper investigates the features of the psychosomatic and vegetative state in patients with GERD and establishes the influence of concomitant obesity on them. Key words: psychoemotional state,…
Hepatotrophic therapy efficiency in the management of a comorbid patient with chronic pancreatitis after etiotropically treated chronic viral hepatitis С
Prof. L.S. Babinets1, prof. O.O. Abrahamovych2 1 I. Horbachevsky Ternopil National Medical University 2 Danylo Halytsky Lviv National Medical University Summary. Relevance. Comorbidity of chronic pancreatitis (CP) and chronic viral hepatitis C (CVHC) is quite common and problematic, even after etiotropic treatment of viral hepatitis C infection. The aim is to investigate the state of…
Features of motor-secretory disorders and distribution of fat tissue in patients with gastroesophageal reflux disease with common obesity
Prof. O.A. Oparin, assoc. prof. Yu.G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. A.E. Novokhatnya, assist. O.M. Kashirttseva Kharkiv National Medical University Ukrainian Humanitarian Institute It has been established that patients with GERD with concomitant obesity have secretory disorders, and in patients with isolated GERD, increased gastric juice aggression comes to the fore, and in…
The influence of secretory activity of adipose tissue adipocytes on the development of gastroesophageal reflux disease
Prof. A.G. Oparin, assoc. prof. L.O. Khomenko, assist. I.P. Korenovsky, assoc. prof. T.M. Oparina, assoc. prof. Y.K. Sikalo. Kharkiv National Medical University Ukrainian Humanitarian Institute The article shows the role of adipose tissue and its hormones in the formation of the pathogenesis of gastroesophageal reflux disease. The role of the hormone leptin in these processes…
Therapeutic effect of peppermint oil application in patients with irritable bowel syndrome and metabolic syndrome
Prof. O.I. Sergienko, assoc. prof. A.I. Сhernobai, assoc. prof. A.Y. Novokhatnia, assoc. prof. A.V. Vlasenko, assoc. prof. Y.K. Sikalo Kharkiv National Medical University Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, affecting almost 20% of the population, causing significant functional and socioeconomic burden. An existing association between functional bowel disorders,…
Analysis of the relationship between the parameters of the autonomic nervous system and the clinical course of type 2 diabetes mellitus in combination with chronic pancreatitis
Prof. L. S. Babinets, asp. O. V. Redkva I.Ya. Horbachevsky Ternopil National Medical University Ministry of Health of Ukraine Abstract. Currently, the possible relationship between the function of the autonomic nervous system (ANS) and type 2 diabetes mellitus (T2DM) is being actively studied. ANS imbalance is also mentioned by researchers as one of the possible…
Construction of a prognotic model of GERD occurrence in overweight people
Prof. A.G. Oparin, assoc. prof. A.E. Novokhatnya, asst. O.M. Kashirttseva, assoc. prof. T.M. Oparina, asst. I.P. Korenovsky, asst. N.A. Yarantseva Kharkiv National Medical University Ukrainian Humanitarian Institute The article reliably recorded high chances of comorbid GERD with obesity with increased blood leptin content (OR = 3.51; 95.0% CI 1.62–612.5; p = 0.023), increased diameter of…
Clinical and anamnestic characteristics and analysis of risk factors of gastroesophageal reflux disease with concomitant obesity in young people
Prof. O.A. Oparin, prof. A.G. Oparin, assoc. prof. A.V. Blagoveshchenska, assoc. prof. Yu.G. Fedchenko, asst. O.M. Kashirttseva, assoc. prof. L.O. Khomenko Kharkiv National Medical University Ukrainian Humanitarian Institute The article analyzes clinical and anamnestic features of patients with gastroesophageal reflex disease with concomitant obesity in young people. Correlations between clinical manifestations and the presence of…
Ultrasound imaging of gastric antrum cancer
Prof. R.Ya. Abdullaev¹, prof. O.A. Oparin², Ph.D. I.V. Krizhanovska¹, assoc. prof. A.V. Blagoveshchenska¹ ¹ Kharkiv National Medical University ² Ukrainian Humanitarian Institute The article presents the results of ultrasound examination in the diagnosis of gastric antral cancer in 43 patients. The diagnosis was established as a result of complex endoscopic, radiological, computed tomography and histological…
Comparative characteristics of the amount of cytokines in patients with hepatitis B and C
First Colonel Huseynov Hamlet Vagif Ministry of Defense of the Republic of Azerbaijan, The chief sanitary doctor of the Azerbaijan Army The problem of viral hepatitis is also important for the Armed Forces, which are the guarantor of the independence of each state. Timely diagnosis of viral hepatitis among new recruits, as well as among…
Pathophysiological and biochemical-molecular concepts of the comorbid course of gastroesophageal reflux disease and obesity in young people
Prof. A.G. Oparin, assoc. prof. Yu. G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. Khomenko, assoc. prof. A.E. Novohatnya, assoc. prof. T.M. Oparina, asp. O.M. Kashirtseva, asst. I.P. Korenovsky Kharkiv National Medical University The article analyzes the latest ideas about the pathogenetic mechanisms of the combined formation of gastroesophageal reflux disease and obesity in young…
The role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflx disease and chronic obstructive pulmonary inflmmation
Prof. O.A. Oparin, PhD. A.V. Blagoveshchenska, PhD. L.O. Khomenko, as. N.V. Semenova, PhD A.E. Novokhatnia, PhD. T.M. Oparina, ass. I.P. Korenovsky Kharkiv National Medical University The paper analyzes the role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflux disease and chronic obstructive pulmonary inflammation. It is shown…
Features of lipid and carbohydrate metabolism in patients with gastroesophageal reflux disease against type 2 diabetes, depending on the presence of obesity
Bondar-Кeleberda O.S. Kharkiv National Medical University The aim: To reveal the peculiarities of lipid and carbohydrate metabolism in patients with isolated gastroesophageal reflex disease (GERD), GERD on the background of type 2 diabetes mellitus (T2DM) and with type 2 DM, depending on the body mass index (BMI). Materials and methods. To participate in the study,…
Current concepts about influence of thyroid gland hormones on the development and course of gastro-esophageal reflux disease
Prof. Oparin O.A., prof. Oparin A.G., asst Yarantseva N.А., assoc. prof. Novokhatnya А.E., assoc. prof. Chomenko L.O., asst. Korenovskiy I.P. Kharkiv National Medical University The problem of gastroesophageal reflux disease (GERD) remains one of the most relevant in modern gastroenterology. In recent decades, there has been a tendency to increase in the incidence of GERD…
Modern understanding of the etiopathogenesis of gastroesophageal reflux disease: clarification of key aspects and perspectives
Prof. Oparin O.A., asst Kashyrtseva O. M., assoc. prof. Oparina T.N., assoc. prof. Sikalo Yu.K. Kharkiv National Medical University Ukrainian Humanitarian Institute Gastroesophageal reflux disease (GERD) is one of the most common diseases among gastroenterological pathologies. The relevance of GERD is due not only to medical aspects, but also to economic ones, since the vast…
Evaluation of the effectiveness of combined treatment in patients with comorbid COPD and GERD
Asp. Semenova N.V., assoc. prof. Oparina T.M. Kharkiv National Medical University Тherapy department №2 Gastroesophageal reflux disease (GERD) is often comorbid with chronic obstructive pulmonary disease (COPD). Such coexisting pathology in the initial stage, which is present in young patients, but poorly studied. The purpose of our study is to study the effectiveness of the…
Endotoxicosis and inflammation as predictors of the deepening of panсreatic functional insufficiency in chronic pancreatitis in combination with type 2 diabetes
Prof. Babinets L.S., asp. Zemlyak O.S., doctorant Halabitska I.M. I.Horbachevsky Ternopil National Medical University According to scientists, a significant role in the progression of chronic pancreatitis (CP) and diabetes mellitus (DM), as well as in the occurrence of complications of these diseases, is played by inflammation and endogenous intoxication by the products of protein breakdown…
Optimization of gastroesophageal reflux disease treatment with concomitant obesity: new approaches and perspectives
Prof. Oparin O.A., Kashyrtseva O.M. Kharkiv National Medical University In recent decades, there has been a rapid increase in obesity among the working-age population. Excess weight is associated with an elevated risk of developing gastrointestinal pathology, including gastroesophageal reflux disease (GERD). The aim of this study was to investigate the effectiveness and rationale for the…