Gout: clinics, diagnostics and treatment.
Prof. О.M. Korzh, PHD S.V. Krasnokutskiy. Kharkiv Medical Academy of Postgraduate Education, Ukraine.
For most patients with gout first contact physicians are general practitioners, family doctors. However, research results indicate a lack of awareness among primary care physicians on the criteria of diagnosis and modern approaches to the treatment of gout. So far most of family physicians traditionally considered gout primarily as “joint” disease. Joint syndrome is a striking clinical manifestation of the disease, affects the quality of life of the patient and acquiring a chronic course, leads to disability. However, within the framework of gout may result in different organs and systems, especially the kidneys, often preceding the typical gouty arthritis and determine the prognosis of the patient. Awareness of family physicians on modern principles of management of patients with gout will improve the early diagnosis of the disease and ensure the timely and optimal treatment. Knowledge of general practitioners risk of violation of purine metabolism underlying gout, and ways of their correction, patient education a healthy lifestyle will provide a basis for effective prevention programs.
Key words: gout, diagnosis and treatment.
Korzh ОM, Krasnokutskiy SV. [Gout: clinics, diagnostics and treatment]. Shidnoevr. z. vnutr. simejnoi med. 2015;1:40-47. Ukrainian.
http://dx.doi.org/10.15407/internalmed2015.01.040
1. Kazimirko VK, Kovalenko VN, authors. [Revmatologiia. Uchebnoe posobie v voprosakh i otvetakh. [Rheumatology. Educational tutorial in questions and answers]. In: Izdatelskii dom Zaslavskii. 2009. 626 p. Russian | ||||
2. Svintsitskyi AS, Yaremenko OB, Puzanova OH, Khomchenkova NI, authors. Revmatychni khvoroby ta syndromy. [Rheumatological diseases and syndroms]. K.: Knyha- plius, 2006. — 680 s. | ||||
3. Klaus B, authors. Klinicheskoe issledovanie kostei, sustavov i myshts. [Clinical examination of bones, joints and muscles]. Meditsinskaia lituratura. 2007. 320 p. Ukrainian | ||||
4. Kovalenko VN, Shuba NM, authors. [Revmaticheskie bolezni: nomenklatura, klassifikatsiia, standarty diagnostiki i lecheniia]. [Rheumatic diseases: nomenclature, classification, standarts of diagnostics and treatment]. K.: OOO «Katran grup». 2004. 212 p. Russian | ||||
5. Maikl D, Dzhon D. Klinicheskaia diagnostika boleznei sustavov. [Clinical diagnostics of joint diseases]. Minsk. 1993. 144 p. Russian | ||||
6. Kevin P, Kennedi L. Diagnostika i lechenie v revmatologii. Problemnyi podkhod. [Diagnostics and treatment in rheumatology. Approaches to problem]. Geotr- Media; 2011. 368 p. Russian | ||||
7. Reutskii IA, Marinin VF, Glotov AV. Diagnostika revmaticheskikh zabolevanii. Rukovodstvo dlia vrachei. [Diagnostics of rheumatic diseases. Guide for doctors]. Meditsinskoe inf. agenstvo; 2011. 440 p. Russian | ||||
8. Siniachenko OV, author. Diagnostika i lechenie boleznei sustavov. [Diagnostics and treatment of joint diseases]. Donetsk; 2012. 560 p. Russian | ||||
9. Siniachenko OV, Barinov EF, authors. Podagra. [Gout]. Donetsk: izd-vo Donetskogo meditsinskogo universiteta; 1994. 247 p. Russian | ||||
10. Kovalenko VN, Bortkevich OP, authors. Revmatologiia. [Rheumatology]. Kiev. 2003. 433 p. Russian | ||||
11. Dalbeth N, So A. Hyperuricemia and gout: state of the art and future perspectives. [Hyperuricemia and gout] Ann. Rheum. Dis. 2010; 69(10): 1738-1743. English http://dx.doi.org/10.1136/ard.2010.136218 |
||||
12. Doria A, Krolewski A. [Lowering serum uric acid levels to prevent kidney failure]. Nature Rev. Nephrology. 2011; 7: 495 — 496. English http://dx.doi.org/10.1038/nrneurol.2011.110 |
||||
13. Harrold IR, Yood RA. [Sex differences in gout epidemiology: evaluation and treatment]. Ann. Rheum. Dis. 2012; 65(10): 1368-1372. English http://dx.doi.org/10.1136/ard.2006.051649 |
||||
14. Kao M. [Allopurinol benefits left ventricular mass and endothelial dysfunction in chronic renal disease] J. Am. Soc. Nephrol.2011; 22: 1382-1389. English http://dx.doi.org/10.1681/ASN.2010111185 |
||||
15. Pascual E, Perdiguero M. [Gout, diuretics and the kidney] Ann. Reum. Dis. 2006; 65(8): 981-982. English http://dx.doi.org/10.1136/ard.2005.049023 |
||||
16. Pascual E, Sivera F. [Why is gout so poorly managed?] Ann. Rheum. Dis. 2007; 66: 1269-1270. English http://dx.doi.org/10.1136/ard.2007.078469 |
||||
17. Roddy E, Zhang W. [Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendation] Ann. Reum. Dis. 2007; 66: 1311-1315. English http://dx.doi.org/10.1136/ard.2007.070755 |
||||
18. Schumacher HR, Becker MA. [Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study ] Rheumatology. 2009; 48: 188-194. English http://dx.doi.org/10.1093/rheumatology/ken457 |