Postcholecystectomy syndrome: a new look at the old problem and the possibilities of pathogenetic therapy

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Prof. Zvyagintseva T.D., Assoc.prof. Chernobay A.I., as. Yaroshenko A.V., prof. Oparin A.G.

Kharkiv National Medical University

In the article, from the modern standpoint, the pathogenetic and clinical characteristics of PCS as a dysfunction of the sphincter of Oddi are given, the mechanisms for the development of this pathology, the principles of therapy with the inclusion of the drug Rowachol, containing six plant monoterpenes, are disclosed. The materials of our own observations of the treatment of patients with Oddi sphincter dysfunction after laparoscopic cholecystectomy by Rowachol are presented. Anti-inflammatory, litholytic, hypocholesterolemic and pleiotropic effects of Rowachol have been proved. Rowachol should be positioned as a pathogenetic natural remedy for treatment of Oddi sphincter dysfunction and biliary sludge in patients undergoing cholecystectomy for cholelithiasis.

Keywords: laparoscopic cholecystectomy, postcholecystectomy syndrome (PCS), Oddi sphincter dysfunction, monoterpenes, Rowachol

https://doi.org/10.15407/internalmed2023.01.067

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Звягінцева, Т.Д. Постхолецистектомічний синдром: новий погляд на давню проблему та можливості патогенетичної терапії / Т.Д. Звягінцева,  А.І. Чернобай, А.В. Ярошенко, А.Г. Опарін // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2023. – № 1. – С. 67-77. doi: 10.15407/internalmed2023.01.067

Zviahintseva TD, Chernobai AI, Yaroshenko AV, Oparin AG. Postkholetsystektomichnyi syndrom: novyi pohliad na davniu problemu ta mozhlyvosti patohenetychnoi terapii [Postcholecystectomy syndrome: a new look at the old problem and the possibilities of pathogenetic therapy]. Shidnoevr. z. vnutr. simejnoi med. 2023;1:67-77. Ukrainian. doi: 10.15407/internalmed2023.01.067

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