Functional dyspepsia (according to the materials of the European guidelines)

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Prof. Sergienko O.I., prof. Oparin O.A.  

Kharkiv National Medical University

Functional dyspepsia (FD) is a common disorder of the interaction between the gastrointestinal tract and the brain, affecting approximately 7% of people in the community. In recent times, significant progress has been made in understanding the complex pathophysiology and new evidence has been obtained regarding the occurrence of FD, with the appearance of the Rome IV criteria, the diagnostic criteria and classification of the disease have been clarified. The British Gastroenterological Society in 2022 has published a guideline with evidence-based recommendations for the diagnosis and management of patients with FD. The article is devoted to the review of European recommendations on the problem of FD.

Keywords: functional dyspepsia, diagnosis, treatment

https://doi.org/10.15407/internalmed2023.01.004

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Сергієнко, О.І. Функціональна диспепсія (за матеріалами європейських настанов) / О.І. Сергієнко, О.А. Опарін // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2023. – № 1. – С. 4-10. doi: 10.15407/internalmed2023.01.004

Serhiyenko OI, Oparin OA. Funktsionalna dyspepsiia (za materialamy yevropeiskykh nastanov) [Functional dyspepsia (according to the materials of the European guidelines)]. Shidnoevr. z. vnutr. simejnoi med. 2023;1:4-10. Ukrainian. doi: 10.15407/internalmed2023.01.004

References:

  1. Ford A, Forman D, Bailey A, Axon A, Moayyedi P. Effect of Dyspepsia on Survival: A Longitudinal 10-Year Follow-Up Study. American Journal of Gastroenterology. 2012;107(6):912-921. http://dx.doi.org/10.1038/ajg.2012.69
  2. Klausen K, Bomme Høgh M, David M, Schaffalitzky de Muckadell O, Hansen J. How dyspepsia, gastroesophageal reflux symptoms, and overlapping symptoms affect quality of life, use of health care, and medication – a long-term population based cohort study. Scandinavian Journal of Gastroenterology. 2021;56(7):753-760. http://dx.doi.org/10.1080/00365521.2021.1929448
  3. Aziz I, Palsson O, Törnblom H, Sperber A, Whitehead W, Simrén M. Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional population-based study. The Lancet Gastroenterology & Hepatology. 2018;3(4):252-262. http://dx.doi.org/10.1016/s2468-1253(18)30003-7
  4. Colin-Jones D, Bloom B, Bodemar G. Management of dyspepsia: report of a working Party. Lancet1988;1:576–9. https://doi.org/10.1016/S0140-6736(88)91364-5
  5. Stanghellini V, Chan F, Hasler W, Malagelada J, Suzuki H, Tack J, Talley N. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-1392. http://dx.doi.org/10.1053/j.gastro.2016.02.011
  6. Moayyedi P, Talley N, Fennerty M, Vakil N. Can the Clinical History Distinguish Between Organic and Functional Dyspepsia?. JAMA. 2006;295(13):1566. http://dx.doi.org/10.1001/jama.295.13.1566
  7. Ford A, Marwaha A, Lim A, Moayyedi P. What Is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology. 2010;8(10):830-837.e2. http://dx.doi.org/10.1016/j.cgh.2010.05.031
  8. Black C, Paine P, Agrawal A, Aziz I, Eugenicos M, Houghton L, Hungin P, Overshott R, Vasant D, Rudd S, Winning R, Corsetti M, Ford A. British Society of Gastroenterology guidelines on the management of functional dyspepsia. Gut. 2022;71(9):1697-1723. http://dx.doi.org/10.1136/gutjnl-2022-327737
  9. Howick J, Phillips B, Ball C. Oxford centre for evidence-based medicine levels of evidence University of Oxford, Centre for Evidence-Based Medicine. 2009;:.
  10. Guyatt G, Oxman A, Akl E, Kunz R, Vist G, Brozek J, Norris S, Falck-Ytter Y, Glasziou P, deBeer H. GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables. Journal of Clinical Epidemiology. 2011;64(4):383-394. http://dx.doi.org/10.1016/j.jclinepi.2010.04.026
  11. Clauwaert N, Jones M, Holvoet L, Vandenberghe J, Vos R, Tack J, Van Oudenhove L. Associations between gastric sensorimotor function, depression, somatization, and symptom-based subgroups in functional gastroduodenal disorders: are all symptoms equal?. Neurogastroenterology & Motility. 2012;24(12):1088-e565. http://dx.doi.org/10.1111/j.1365-2982.2012.01985.x
  12. Fang Y, Liou J, Chen C, Lee J, Hsu Y, Chen M, Tseng P, Chen C, Chang C, Yang T, Chang W, Wu J, Wang H, Luo J, Lin J, Shun C, Wu M. Distinct aetiopathogenesis in subgroups of functional dyspepsia according to the Rome III criteria. Gut. 2014;64(10):1517-1528. http://dx.doi.org/10.1136/gutjnl-2014-308114
  13. Palsson O, Whitehead W, van Tilburg M. Development and validation of the Rome IV diagnostic questionnaire for adults. Gastroenterology 2016;150:1481–91.
  14. Drossman D, Tack J. Rome Foundation Clinical Diagnostic Criteria for Disorders of Gut-Brain Interaction. Gastroenterology. 2022;162(3):675-679. http://dx.doi.org/10.1053/j.gastro.2021.11.019
  15. Barberio B, Mahadeva S, Black C, Savarino E, Ford A. Systematic review with meta-analysis: global prevalence of uninvestigated dyspepsia according to the Rome criteria. Alimentary Pharmacology & Therapeutics. 2020;52(5):762-773. http://dx.doi.org/10.1111/apt.16006
  16. Sperber A, Bangdiwala S, Drossman D. Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation global study. Gastroenterology. 2021;160:99–114
  17. Ford A, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2014;64(7):1049-1057. http://dx.doi.org/10.1136/gutjnl-2014-307843
  18. Moayyedi P, Forman D, Braunholtz D, Feltbower R, Crocombe W, Liptrott M, Axon A. The proportion of upper gastrointestinal symptoms in the community associated with helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs. The American Journal of Gastroenterology. 2000;95(6):1448-1455. http://dx.doi.org/10.1111/j.1572-0241.2000.2126_1.x
  19. Aziz I, Palsson O, Törnblom H, Sperber A, Whitehead W, Simrén M. Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional population-based study. The Lancet Gastroenterology & Hepatology. 2018;3(4):252-262. http://dx.doi.org/10.1016/s2468-1253(18)30003-7
  20. Ford A, Marwaha A, Lim A, Moayyedi P. 973 Prevalence of Irritable Bowel Syndrome in Individuals with Dyspepsia: Systematic Review and Meta-Analysis. Gastroenterology. 2009;136(5):A-149. http://dx.doi.org/10.1016/s0016-5085(09)60671-5
  21. Aro P, Talley N, Johansson S. Anxiety is linked to newonset dyspepsia in the Swedish population: a 10-year followup study. Gastroenterology. 2015;148:928–37. https://doi.org/10.1053/j.gastro.2015.01.039
  22. Talley N, Fett S, Zinsmeister A, Melton L. Gastrointestinal tract symptoms and self-reported abuse: A population-based study. Gastroenterology. 1994;107(4):1040-1049. http://dx.doi.org/10.1016/0016-5085(94)90228-3
  23. Futagami S, Itoh T, Sakamoto C. Systematic review with meta-analysis: post-infectious functional dyspepsia. Alimentary Pharmacology & Therapeutics. 2014;41(2):177-188. http://dx.doi.org/10.1111/apt.13006
  24. Bytzer P. Low socioeconomic class is a risk factor for upper and lower gastrointestinal symptoms: a population based study in 15 000 Australian adults. Gut. 2001;49(1):66-72. http://dx.doi.org/10.1136/gut.49.1.66
  25. Schol J, Wauters L, Dickman R, Drug V, Mulak A, Serra J, Enck P, Tack J. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis. Neurogastroenterology & Motility. 2021;33(8):. http://dx.doi.org/10.1111/nmo.14237
  26. Jones R. Primary care research and clinical practice: gastroenterology. Postgraduate Medical Journal. 2008;84(995):454-458. http://dx.doi.org/10.1136/pgmj.2008.068361
  27. Ford A, Forman D, Bailey A, Axon A, Moayyedi P. Initial poor quality of life and new onset of dyspepsia: results from a longitudinal 10-year follow-up study. Gut. 2007;56(3):321-327. http://dx.doi.org/10.1136/gut.2006.099846
  28. Jefferies E, Brewster S. Urological recommendations from the National Institute for Health and Care Excellence (NICE) Guideline, June 2015: Suspected cancer: recognition and referral. BJU International. 2015;117(6):857-860. http://dx.doi.org/10.1111/bju.13355
  29. Stapley S, Peters T, Neal R, Rose P, Walter F, Hamilton W. The risk of pancreatic cancer in symptomatic patients in primary care: a large case–control study using electronic records. British Journal of Cancer. 2012;106(12):1940-1944. http://dx.doi.org/10.1038/bjc.2012.190
  30. Corsetti M, Caenepeel P, Fischler B, Janssens J, Tack J. Impact of Coexisting Irritable Bowel Syndrome on Symptoms and Pathophysiological Mechanisms in Functional Dyspepsia. The American Journal of Gastroenterology. 2004;99(6):1152-1159. http://dx.doi.org/10.1111/j.1572-0241.2004.30040.x
  31. Aziz I, Palsson O, Törnblom H, Sperber A, Whitehead W, Simrén M. The Prevalence and Impact of Overlapping Rome IV-Diagnosed Functional Gastrointestinal Disorders on Somatization, Quality of Life, and Healthcare Utilization: A Cross-Sectional General Population Study in Three Countries. American Journal of Gastroenterology. 2018;113(1):86-96. http://dx.doi.org/10.1038/ajg.2017.421
  32. Geeraerts A, Van Houtte B, Clevers E, Geysen H, Vanuytsel T, Tack J, Pauwels A. Gastroesophageal Reflux Disease—Functional Dyspepsia Overlap: Do Birds of a Feather Flock Together?. American Journal of Gastroenterology. 2020;115(8):1167-1182. http://dx.doi.org/10.14309/ajg.0000000000000619
  33. Schol J, Wauters L, Dickman R, Drug V, Mulak A, Serra J, Enck P, Tack J. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis. Neurogastroenterology & Motility. 2021;33(8): http://dx.doi.org/10.1111/nmo.14237
  34. Sugano K, Tack J, Kuipers E, Graham D, El-Omar E, Miura S, Haruma K, Asaka M, Uemura N, Malfertheiner P. Kyoto global consensus report on Helicobacter pylori Gut. 2015;64(9):1353-1367. http://dx.doi.org/10.1136/gutjnl-2015-309252
  35. Ghoshal U, Ghoshal U, Rahman M, Mathur A, Rai S, Akhter M, Mostafa T, Islam M, Haque S, Pandey A, Kibria M, Ahmed F. Post‐infection functional gastrointestinal disorders following coronavirus disease‐19: A case–control study. Journal of Gastroenterology and Hepatology. 2021;37(3):489-498. http://dx.doi.org/10.1111/jgh.15717
  36. Talley N, Powell N, Walker M, Jones M, Ronkainen J, Forsberg A, Kjellström L, Hellström P, Aro P, Wallner B, Agréus L, Andreasson A. Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population‐based studies. Alimentary Pharmacology & Therapeutics. 2021;54(1):32-42. http://dx.doi.org/10.1111/apt.16372