Prof. Korzh O.M., PHD Korzh I.V.*
Kharkiv Medical Academy of Postgraduate Education
*Sytenko Institute of Spine and Joint Pathology of National Academy of Medical Sciences of Ukraine
Osteoarthritis is a serious interdisciplinary problem that is relevant for a number of clinical specialties: therapists, rheumatologists, orthopedists, professional pathologists. Modern research on this problem indicates the pronounced heterogeneity of osteoarthritis, associated with a variety of clinical forms and risk factors of the disease. Occupation can be a significant additional risk factor that contributes to the accelerated development of the disease, including after termination of contact with a harmful industrial factor. Comprehensive analysis of risk factors for the development and progression of osteoarthritis, including professional activity, is important from the point of view of prevention and treatment of the disease.
Key words: osteoarthritis, diagnosis, family doctor.
https://dx.doi.org/10.15407/internalmed2022.02.086
Cite:
- Корж, О.М. Остеоартрит у практиці сімейного лікаря: диференційно-діагностичні аспекти / О.М. Корж, І.В. Корж // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2022. – № 2. – С. 86-90. doi: 15407/internalmed2022.02.086
- Korzh OM, Korzh IV. [Osteoarthritis in the practice of a family doctor: differential diagnostic aspects]. Shidnoevr. z. vnutr. simejnoi med. 2022;2:86-90. Ukrainian. doi: 10.15407/internalmed2022.02.086
References
- Maradit Kremers H, Larson D, Crowson C, Kremers W, Washington R, Steiner C, Jiranek W, Berry D. Prevalence of Total Hip and Knee Replacement in the United States. The Journal of Bone and Joint Surgery-American Volume. 2015;97(17):1386-1397. http://dx.doi.org/10.2106/jbjs.n.01141
- Palsis J, Brehmer T, Pellegrini V, Drew J, Sachs B. The Cost of Joint Replacement. Journal of Bone and Joint Surgery. 2018;100(4):326-333. http://dx.doi.org/10.2106/jbjs.17.00161
- Lespasio M, Piuzzi N, Husni M, Muschler G, Guarino A, Mont M. Knee Osteoarthritis: A Primer. The Permanente Journal. 2017;21(4):. http://dx.doi.org/10.7812/tpp/16-183
- Buckwalter J, Mankin H, Grodzinsky A. Articular cartilage and Osteoarthritis. Instr. Course Lect. 2005;54:465-480.
- Brandt K, Dieppe P, Radin E. Etiopathogenesis of Osteoarthritis. Medical Clinics of North America. 2009;93(1):1-24. http://dx.doi.org/10.1016/j.mcna.2008.08.009
- Wieland H, Michaelis M, Kirschbaum B, Rudolphi K. Osteoarthritis — an untreatable disease?. Nature Reviews Drug Discovery. 2005;4(4):331-344. http://dx.doi.org/10.1038/nrd1693
- Poulet B, Hamilton R, Shefelbine S, Pitsillides A. Characterizing a novel and adjustable noninvasive murine joint loading model. Arthritis & Rheumatism. 2010;63(1):137-147. http://dx.doi.org/10.1002/art.27765
- Yu H, Huang T, Lu W, Tong L, Chen D. Osteoarthritis Pain. International Journal of Molecular Sciences. 2022;23(9):4642. http://dx.doi.org/10.3390/ijms23094642
- Zhang Y, Nevitt M, Niu J, Lewis C, Torner J, Guermazi A, Roemer F, McCulloch C, Felson D. Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging. Arthritis & Rheumatism. 2011;63(3):691-699. http://dx.doi.org/10.1002/art.30148
- Adatia A, Rainsford K, Kean W. Osteoarthritis of the knee and hip. Part I: aetiology and pathogenesis as a basis for pharmacotherapy. Journal of Pharmacy and Pharmacology. 2012;64(5):617-625. http://dx.doi.org/10.1111/j.2042-7158.2012.01458.x
- Neogi T. Clinical significance of bone changes in osteoarthritis. Arthritis Research & Therapy. 2012;14(S2):. http://dx.doi.org/10.1186/ar3710
- Li G, Yin J, Gao J, Cheng T, Pavlos N, Zhang C, Zheng M. Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes. Arthritis Research & Therapy. 2013;15(6):223. http://dx.doi.org/10.1186/ar4405
- Hargrave-Thomas E, van Sloun F, Dickinson M, Broom N, Thambyah A. Multi-scalar mechanical testing of the calcified cartilage and subchondral bone comparing healthy vs early degenerative states. Osteoarthritis and Cartilage. 2015;23(10):1755-1762. http://dx.doi.org/10.1016/j.joca.2015.05.012
- Vincent K, Vasilopoulos T, Montero C, Vincent H. Eccentric and Concentric Resistance Exercise Comparison for Knee Osteoarthritis. Medicine & Science in Sports & Exercise. 2019;51(10):1977-1986. http://dx.doi.org/10.1249/mss.0000000000002010
- Fang H, Huang L, Welch I, Norley C, Holdsworth D, Beier F, Cai D. Early Changes of Articular Cartilage and Subchondral Bone in The DMM Mouse Model of Osteoarthritis. Scientific Reports. 2018;8(1):. http://dx.doi.org/10.1038/s41598-018-21184-5
- Amini M, Nazemi S, Lanovaz J, Kontulainen S, Masri B, Wilson D, Szyszkowski W, Johnston J. Individual and combined effects of OA-related subchondral bone alterations on proximal tibial surface stiffness: a parametric finite element modeling study. Medical Engineering & Physics. 2015;37(8):783-791. http://dx.doi.org/10.1016/j.medengphy.2015.05.011
- Castañeda S, Roman-Blas J, Largo R, Herrero-Beaumont G. Subchondral bone as a key target for osteoarthritis treatment. Biochemical Pharmacology. 2012;83(3):315-323. http://dx.doi.org/10.1016/j.bcp.2011.09.018
- Goldring M, Goldring S. Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Annals of the New York Academy of Sciences. 2010;1192(1):230-237. http://dx.doi.org/10.1111/j.1749-6632.2009.05240.x
- Cisternas M, Murphy L, Sacks J, Solomon D, Pasta D, Helmick C. Alternative Methods for Defining Osteoarthritis and the Impact on Estimating Prevalence in a US Population-Based Survey. Arthritis Care & Research. 2016;68(5):574-580. http://dx.doi.org/10.1002/acr.22721
- Caine D, Golightly Y. Osteoarthritis as an outcome of paediatric sport: an epidemiological perspective. British Journal of Sports Medicine. 2011;45(4):298-303. http://dx.doi.org/10.1136/bjsm.2010.081984
- Murphy L, Helmick C. The Impact of Osteoarthritis in the United States. Orthopaedic Nursing. 2012;31(2):85-91. http://dx.doi.org/10.1097/nor.0b013e31824fcd42
- Felson D. The epidemiology of knee osteoarthritis: Results from the framingham osteoarthritis study. Seminars in Arthritis and Rheumatism. 1990;20(3):42-50. http://dx.doi.org/10.1016/0049-0172(90)90046-i
- Berenbaum F, Wallace I, Lieberman D, Felson D. Modern-day environmental factors in the pathogenesis of osteoarthritis. Nature Reviews Rheumatology. 2018;14(11):674-681. http://dx.doi.org/10.1038/s41584-018-0073-x
- Felson D, Goggins J, Niu J, Zhang Y, Hunter D. The effect of body weight on progression of knee osteoarthritis is dependent on alignment. Arthritis & Rheumatism. 2004;50(12):3904-3909. http://dx.doi.org/10.1002/art.20726
- Wang P, Guan P, Guo C, Zhu F, Konstantopoulos K, Wang Z. Fluid shear stress‐induced osteoarthritis: roles of cyclooxygenase‐2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases. The FASEB Journal. 2013;27(12):4664-4677. http://dx.doi.org/10.1096/fj.13-234542
- Ezzat A, Li L. Occupational Physical Loading Tasks and Knee Osteoarthritis: A Review of the Evidence. Physiotherapy Canada. 2014;66(1):91-107. http://dx.doi.org/10.3138/ptc.2012-45bc
- Caine D, Meyers R, Nguyen J, Schöffl V, Maffulli N. Primary Periphyseal Stress Injuries in Young Athletes: A Systematic Review. Sports Medicine. 2021;52(4):741-772. http://dx.doi.org/10.1007/s40279-021-01511-z
- Sharma L. Osteoarthritis of the Knee. New England Journal of Medicine. 2021;384(1):51-59. http://dx.doi.org/10.1056/nejmcp1903768