Features of the clinical course and motorsecretory disorders in gastroesophageal reflux disease in overweight patients.

Prof. Oparin O.A., Maliar O.M., Fedchenko Yu.G.

Kharkiv Medical Academy of Postgraduate Education

Objective: To study the mechanisms of motor-secretory disorders in young patients with gastroesophageal reflux disease with concomitant obesity.

Materials and results. The study involved 55 patients. The first group included patients with GERD with concomitant obesity, the second group included patients with GERD without concomitant pathology, the control group – 20 healthy people. The survey was conducted using the GERDQ questionnaire. The results showed that complaints of regurgitation, belching and dysphagia were more pronounced in obese GERD patients. Motor-secretory disturbances were examined by ultrasound and pH-metry, with indicators of the diameter of the esophageal orifice of the diaphragm, dilation of the lower third of the esophagus, reflux volume, acidity of gastric contents significantly higher in patients with GERD with concomitant obesity. The correlation between body mass index, severity of complaints and indicators of motor-secretory disorders was revealed.

Key words: gastroesophageal reflux disease, GERD, obesity, motor-secretory disorders, pH-metry.


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1. Oparin, O.A. Features of the clinical course and motorsecretory disorders in gastroesophageal reflux disease in overweight patients / O.A. Oparin, O.M. Maliar, Yu.G.Fedchenko // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2021. – №1. – С. 127-130. doi: 10.15407/internalmed2021.01.127

2. Oparin OA, Maliar OM, Fedchenko YuG. Features of the clinical course and motorsecretory disorders in gastroesophageal reflux disease in overweight patients. Shidnoevr. z. vnutr. simejnoi med. 2021;1:127-130. doi: 10.15407/internalmed2021.01.127


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