Age and gender features of clinical course COVID-19.

Prof. Kovalyova O.M.

Kharkiv National Medical University

 The article presents the review of modern publications devoted the assessment the impact of age and gender on susceptibility, clinical manifestation and outcome of COVID-19 infection. Statistical data on rate of COVID-19 in relation to age categories and adverse clinical signs of disease in different populations are shown. Old and older ages are the predictors of severe coronavirus course and mortality are emphasized. Gender features of coronavirus infection have been described according to gender cardiology with taken in account the disproportion of hypertension and coronary heart disease in male and female. Due to the scientific research the gender and age peculiarities of immune response to virus infection is considered. The definition of hypothesis “immunosenescence” underlying adverse outcome due to COVID-19 in older patients is taken. Gender peculiarities of COVID-19 are presented by evident scientific data according to the relationship between sex hormone and immune inflammation factors.

Key Words: coronavirus disease COVID-19, age and gender, gender cardiology, immune responses to infection, sex hormons.

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  1. Ковальова, О.М. Вікові та гендерні особливості клінічного перебігу коронавірусної хвороби COVID-19 // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2021. – № 2. – С. 4-9. doi: 10.15407/internalmed2021.02.004
  2. Kovalyova OM. Vikovi ta henderni osoblyvosti klinichnoho perebihu koronavirusnoi khvoroby COVID-19. [Age and gender features of clinical course COVID-19]. Shidnoevr. z. vnutr. simejnoi med. 2021;2:4-9. Ukrainian. doi: 10.15407/internalmed2021.02.004


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