Modern possibilities of diagnosis and quantification of liver fibrosis.

Modern possibilities of diagnosis and quantification of liver fibrosis.

PHD A. Zhuravlyova, PHD O. Ogneva. Kharkiv National Medical University.

This article is devoted to modern possibilities of early diagnosis of liver fibrosis. Liver fibrosis appears in response to a prolonged chronic liver disease of any origin and further may cause liver cirrhosis and hepatocellular carcinoma. Recently it became known that fibrosis is a dynamic process with a potential opportunity to reverse. Therefore, the definition of its early stages is now very important and can greatly influence the further course of the disease.

Key Words: liver fibrosis, liver needle biopsy, serum fibrosis markers.

Zhuravlyova AK, Ogneva OV. [Modern possibilities of diagnosis and quantification of liver fibrosis]. Shidnoevr. z. vnutr. simejnoi med. 2015;2:55-60. Russian.
http://dx.doi.org/10.15407/internalmed2015.02.055

Download.PDF

1. Manning DS, Afdhal NH [Diagnosis and Quantification of fibrosis] Gastroenterology. 2008; 134 (6): 1670-1681. English
http://dx.doi.org/10.1053/j.gastro.2008.03.001
2. Regev A, Berho M, Jeffers LJ. [Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection] Am J Gastroenterol. 2002; 97: 2614—2618. English
http://dx.doi.org/10.1111/j.1572-0241.2002.06038.x
3. Lindor KD, Bru C, Jorgensen RA. [The role of ultrasonography and automatic-needle biopsy in outpatient percutaneous liver biopsy] Hepatology. 1996; 23: 1079— 1083. English
http://dx.doi.org/10.1002/hep.510230522
4. Thampanitchawong P, Piratvisuth T. [Liver biopsy: complications and risk factors] World J Gastroenterol. 1999; 5: 301—304. English
http://dx.doi.org/10.3748/wjg.v5.i4.301
5. Terjung B, Lemnitzer I, Dumoulin FL. [Bleeding complications after percutaneous liver biopsy (An analysis of risk factors)] Digestion. 2003; 67: 138—145. English
http://dx.doi.org/10.1159/000071293
6. Poniachik J, Bernstein DE, Reddy KR. [The role of laparoscopy in the diagnosis of cirrhosis]. Gastrointest Endosc. 1996; 43: 568—571. English
http://dx.doi.org/10.1016/S0016-5107(96)70192-X
7. Bedossa P, Dargere D, Paradis V. [Sampling variability of liver fibrosis in chronic hepatitis C]. Hepatology. 2003; 38: 1449—1457. English
http://dx.doi.org/10.1053/jhep.2003.09022
8. OBrien MJ, Keating NM, Elderiny S. [An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C]. Am J Clin Pathol. 2000; 114: 712—718. English
9. Parkes J, Guha IN, Roderick P. [Performance of serum marker panels for liver fibrosis in chronic hepatitis C]. J Hepatol. 2006; 44: 462—474. English
http://dx.doi.org/10.1016/j.jhep.2005.10.019
10. Imbert-Bismut F, Ratziu V, Pieroni L. [Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study]. Lancet. 2001; 357: 1069—1075. English
http://dx.doi.org/10.1016/S0140-6736(00)04258-6
11. Thabut D, Simon M, Myers RP. [Noninvasive prediction of fibrosis in patients with chronic hepatitis] Hepatology. 2003; 37: 1220—1221. English
http://dx.doi.org/10.1053/jhep.2003.50109
12. Wai CT, Greenson JK, Fontana RJ. [A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C]. Hepatology. 2003; 38: 518—526. English
http://dx.doi.org/10.1053/jhep.2003.50346
13. Anderson FH, Zeng L, Rock NR. [An assessment of the clinical utility of serum ALT and AST in chronic hepatitis C]. Hepatol Res. 2000; 18: 63—71. English
http://dx.doi.org/10.1016/S1386-6346(99)00085-6
14. Park GJ, Lin BP, Ngu MC. [Aspartate aminotransferase: alanine aminotransferase ratio in chronic hepatitis C infection: is it a useful predictor of cirrhosis?]. J GastroenterolHepatol. 2000; 15: 386—390. English
http://dx.doi.org/10.1046/j.1440-1746.2000.02172.x
15. Kawasaki T, Takeshita A, Souda K. [Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis]. Am J Gastroenterol. 1999; 94: 1918—1922. English
http://dx.doi.org/10.1111/j.1572-0241.1999.01231.x
16. Shaheen AA, Myers RP. [Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: a systematic review]. Hepatology. 2007; 46: 912—921. English
http://dx.doi.org/10.1002/hep.21835
17. Teare JP, Sherman D, Greenfield SM. [Comparison of serum procollagen III peptide concentrations and PGA index for assessment of hepatic fibrosis]. Lancet. 1993; 342: 895—898. English
http://dx.doi.org/10.1016/0140-6736(93)91946-J
18. Rossi E, Adams L, Prins A. [Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients]. Clin Chem. 2003; 49: 450—454. English
http://dx.doi.org/10.1373/49.3.450
19. Poynard T, Morra R, Halfon P. [Meta-analyses of Fibrotest diagnostic value in chronic liver disease]. BMC Gastroenterol. 2007; 7: 40 English
http://dx.doi.org/10.1186/1471-230X-7-40
20. Pares A, Deulofeu R, Gimenez A. [Serum hyaluronate reflects hepatic fibrogenesis in alcoholic liver disease and is useful as a marker of fibrosis]. Hepatology. 1996; 24: 1399—1403. English
http://dx.doi.org/10.1002/hep.510240615
21. Giannini E, Caglieris S, Ceppa P. [Serum pro-collagen III peptide levels are related to lobular necrosis in untreated patients with chronic hepatitis C]. Eur J Gastroenterol Hepatol. — 2001; 13: 137—141. English
http://dx.doi.org/10.1097/00042737-200102000-00008
22. Khan S, Subedi D, Chowdhury MM. [Use of amino terminal type III procollagen peptide (P3NP) assay in methotrexate therapy for psoriasis]. Postgrad Med J. 2006; 82: 353—354. English
http://dx.doi.org/10.1136/pgmj.2005.041533
23. Boeker KH, Haberkorn CI, Michels D. [Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C]. ClinChimActa. 2002; 316: 71—81. English
http://dx.doi.org/10.1016/S0009-8981(01)00730-6
24. Larrousse M, Laguno M, Segarra M. [Noninvasive diagnosis of hepatic fibrosis in HIV/HCV-coinfected patients]. J Acquir Immune DeficSyndr. 2007; 46: 304—311. English
http://dx.doi.org/10.1097/QAI.0b013e3181520502
25. McClain CJ, Cohen DA. [Increased tumor necrosis factor production by monocytes in alcoholic hepatitis]. Hepatology. 1989; 9: 349—351. English
http://dx.doi.org/10.1002/hep.1840090302
26. Ikura Y, Morimoto H, Ogami M. [Expression of platelet-derived growth factor and its receptor in livers of patients with chronic liver disease]. J Gastroenterol. 1997; 32: 496—501. English
http://dx.doi.org/10.1007/BF02934089
27. Rosenberg WM, Michael V, Robert T. [Serum markers detect the presence of liver fibrosis: A cohort study]. Gastroenterology. 2012; 127 (6): 1704-1713. English
http://dx.doi.org/10.1053/j.gastro.2004.08.052
28. Kelleher TB, Mehta SH, Bhaskar R. [Prediction of hepatic fibrosis in HIV/HCV co-infected patients using serum fibrosis markers: the SHASTA index]. J Hepatol. 2005; 43: 78—84. English
http://dx.doi.org/10.1016/j.jhep.2005.02.025
29. Honda H, Onitsuka H, Masuda K. [Chronic liver disease: value of volumetry of liver and spleen with computed tomography]. Radiat Med. 1990; 8: 222—226. English
30. Kettaneh A, Marcellin P, Douvin C. [Features associated with success rate and performance of FibroScan measurements for the diagnosis of cirrhosis in HCV patients: a prospective study of 935 patients]. J Hepatol. 2007; 46: 628—634. English
http://dx.doi.org/10.1016/j.jhep.2006.11.010
31. Ziol M, Handra-Luca A, Kettaneh A. [Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C]. Hepatology. 2005; 41: 48—54. English
http://dx.doi.org/10.1002/hep.20506
32. Talwalkar JA, Kurtz DM, Schoenleber SJ. [Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis]. ClinGastroenterolHepatol. 2007; 5: 1214—1220. English
http://dx.doi.org/10.1016/j.cgh.2007.07.020
33. Shaheen AA, Wan AF, Myers RP. [FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy]. Am J Gastroenterol. 2007; 102: 2589—2600. English
http://dx.doi.org/10.1111/j.1572-0241.2007.01466.x
34. Huwart L, Peeters F, Sinkus R. [Liver fibrosis: noninvasive assessment with MR elastography]. NMR Biomed. 2006; 19: 173—179. English
http://dx.doi.org/10.1002/nbm.1030
35. Yin M, Talwalkar JA, Glaser KJ. [Assessment of hepatic fibrosis with magnetic resonance elastography]. ClinGastroenterolHepatol. 2007; 5: 1207—1213. English
http://dx.doi.org/10.1016/j.cgh.2007.06.012