Association between comorbid conditions and mortality of patients administred to the intensive care unit in acute exacerbations of chronic obstructive pulmonary disease.

T. Abbasalieva, Jebrail T. Mammadov, Jeyhun M. Ismayilzadа, Gunel B. Sadigova.

Azerbaijan Medical University, Baku, Azerbaijan.

Introduction. Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients with COPD often require admission to intensive care units (ICU) during an acute exacerbation.Aim. Our study aimed to identify somecomorbidities independently associated with hospital mortality in patients requiring ICU admission for acute exacerbation of COPD.Methods. Previously diagnosed COPD patients were admitted to the ICU. Patients` demographics, comorbidities, body mass index, arterial blood gas results were investigated. Patients were grouped according to mortality (survival and non-survival), and all the variables were compared between the two groups.Results. Comorbidities of the non-survival group (female-male, 1/19) were different compared with the survival group (female-male, 1/31): diabetes mellitus (15% vs 18,8%), heart failure (20,0% vs 18,8%), Cor- pulmonale (75,0% vs 37,5%), troponin (35,0% vs 31,2%) (р=0,728, р=0,911, р=0,008, р=0,779).Conclusion. In the present study Cor-pulmonale, GOLD-D patients, patients age were independent factors associated with in-hospital mortality for patients admitted to ICU for acute exacerbations of COPD.

Key Words: Chronic obstructive pulmonary disease, comorbidity, intensive care unit.