Prof. O.A. Oparin, assoc. prof. Yu.G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. A.E. Novokhatnya, assist. O.M. Kashirttseva Kharkiv National Medical University Ukrainian Humanitarian Institute It has been established that patients with GERD with concomitant obesity have secretory disorders, and in patients with isolated GERD, increased gastric juice aggression comes to the fore, and in…
Obesity
Arterial hypertension in obese patients: clinical and pathogenetic features
Prof. O.M. Korzh, prof. L.V. Cherkashyna, assoc. prof. L.M. Tsogoeva Kharkiv National Medical University Induced arterial hypertension (AH) is one of the forms of AH, the pathogenetic mechanisms of which are well studied: the main reason is the disruption of the functioning of visceral adipose tissue, which leads to activation of the renin-angiotensin-aldosterone system, imbalance…
Construction of a prognotic model of GERD occurrence in overweight people
Prof. A.G. Oparin, assoc. prof. A.E. Novokhatnya, asst. O.M. Kashirttseva, assoc. prof. T.M. Oparina, asst. I.P. Korenovsky, asst. N.A. Yarantseva Kharkiv National Medical University Ukrainian Humanitarian Institute The article reliably recorded high chances of comorbid GERD with obesity with increased blood leptin content (OR = 3.51; 95.0% CI 1.62–612.5; p = 0.023), increased diameter of…
Clinical and anamnestic characteristics and analysis of risk factors of gastroesophageal reflux disease with concomitant obesity in young people
Prof. O.A. Oparin, prof. A.G. Oparin, assoc. prof. A.V. Blagoveshchenska, assoc. prof. Yu.G. Fedchenko, asst. O.M. Kashirttseva, assoc. prof. L.O. Khomenko Kharkiv National Medical University Ukrainian Humanitarian Institute The article analyzes clinical and anamnestic features of patients with gastroesophageal reflex disease with concomitant obesity in young people. Correlations between clinical manifestations and the presence of…
Pathophysiological and biochemical-molecular concepts of the comorbid course of gastroesophageal reflux disease and obesity in young people
Prof. A.G. Oparin, assoc. prof. Yu. G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. Khomenko, assoc. prof. A.E. Novohatnya, assoc. prof. T.M. Oparina, asp. O.M. Kashirtseva, asst. I.P. Korenovsky Kharkiv National Medical University The article analyzes the latest ideas about the pathogenetic mechanisms of the combined formation of gastroesophageal reflux disease and obesity in young…
Features of lipid and carbohydrate metabolism in patients with gastroesophageal reflux disease against type 2 diabetes, depending on the presence of obesity
Bondar-Кeleberda O.S. Kharkiv National Medical University The aim: To reveal the peculiarities of lipid and carbohydrate metabolism in patients with isolated gastroesophageal reflex disease (GERD), GERD on the background of type 2 diabetes mellitus (T2DM) and with type 2 DM, depending on the body mass index (BMI). Materials and methods. To participate in the study,…
Features of arterial hypertension in obesity
Prof. Korzh O.M. Kharkiv National Medical University Hypertension in obesity is a fairly common problem, and it has its own characteristics. Obesity promotes inflammation in the body, which can damage blood vessels and lead to atherosclerosis, which also contributes to increased blood pressure. Obesity can lead to increased resistance to blood flow in vessels through…
Comorbid patient: an interdisciplinary problem (literature review)
Prof. Kravchun N.O., assoc. prof. Dunaieva I.P., assoc. prof. Yakovenko O.L., prof. Kravchun P.P. Kharkiv National Medical University The comorbidity of arterial hypertension (AH), type 2 diabetes mellitus (T2DM), obesity leads to the early development of atherosclerotic lesions of coronary and cerebral vessels, which, in turn, significantly accelerates the occurrence of coronary arterial disease (CHD),…
Optimization of gastroesophageal reflux disease treatment with concomitant obesity: new approaches and perspectives
Prof. Oparin O.A., Kashyrtseva O.M. Kharkiv National Medical University In recent decades, there has been a rapid increase in obesity among the working-age population. Excess weight is associated with an elevated risk of developing gastrointestinal pathology, including gastroesophageal reflux disease (GERD). The aim of this study was to investigate the effectiveness and rationale for the…
The contribution of some biologically active substances of adipose tissue to the development of cardiovascular complications in comorbid patients
Prof. Kravchun P.P., Assoc.prof. Yakovenko O.L., Assoc.prof. Dunaieva I.P., prof. Kravchun N.O. Kharkiv National Medical University The contribution of some biologically active substances of adipose tissue to the development of cardiovascular complications in comorbid patients. Adipose tissue hormones — adipokines — vaspin and omentin, which control homeostasis, lipid and glucose metabolism, have attracted scientific interest…
The role of adipose tissue hormones in the formation and course of gastroesophageal reflux disease in combination with obesity.
Prof. O.A. Oparin, O.M. Malіar, PHD T.N. Oparina, E. J. Abakumova Kharkiv Medical Academy of Postgraduate Education Objective: To investigate the level of leptin in patients with gastroesophageal reflux disease with concomitant obesity and evaluate its effect on the course of the disease. Materials and results. The study involved 50 patients. The first group included…