Comparative study of some immunological parameters in case of intestinal parasitic invasion in student.

Sh.F. Mamedova

Azerbaijan Medical University, Baku

Department of Infectious diseases

A total of 395 practically healthy students were under our supervision. The control group consisted of 22 healthy students matched by age and sex, without concomitant diseases. The students were between the 17-21. It was revealed in 49- giardiasis, in 46- ascariasis, in 26- enterobiosis, in 67-mixed parasitosis. The mixed group is divided into 4 subgroup: a) giardiasis + ascariasis b) giardiasis + enterobiosis c) giardiasis + ascariasis+ enterobiosis d) ascariasis+ enterobiosis. In addition to some immune parameters, the concentration of IgA, IgM, IgG, IgE was determined. The data, which showed the results of the studies, turned out to be lower: in the blood serum of İl-4, almost 4 times(5,6pg/ml) (р <0,05). Based on the data obtained, in can be concluded that intestinal parasitosis is a factor influencing the immune status of patients with parasitism. Intestinal parasitisms, in particular giardiasis, cause intestinal dysbiosis, inhibit the normal intestinal microflora and weaken the local immunity of the digestive tract, as a result of which conditionally pathogenic flora is activated and pathogenic microorganisms develop.

https://dx.doi.org/10.15407/internalmed2021.02.088

Download.PDF (rus)

Cite:

  1. Мамедова, Ш.Ф. Сравнительное изучение некоторых иммунологических показателей при кишечно-паразитарной инвазии у студентов // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2021. – № 2. – С. 88-90. doi: 15407/internalmed2021.02.088
  2. Mamedova ShF. Sravnitel’noe izuchenie nekotorykh immunologicheskikh pokazatelej pri kishechno-parazitarnoj invazii u studentov. [Comparative study of some immunological parameters in case of intestinal parasitic invasion in student]. Shidnoevr. z. vnutr. simejnoi med. 2021;2:88-90. Russian. doi: 10.15407/internalmed2021.02.088

References:

  1. Parazitologicheskij monitoring v Rossii.Osnovy koncepcii. Parazitologija i parazitarnye bolezni. 1997;1:38-39. Russian
  2. Kramarev SA, Ershova IV, Bondarenko GG. Gel’mintozy u detej i podrostkov. Kiev. Lugansk; 2006.128 р. Russian
  3. Huseynova NM, Mammadova ShF, Garagozova AA. Clinical and immunological peculiaritites of the contemporary current of askaridose, lambliosis, enterobiosis. Azerb. State University Baku, Azerbaijan. Medical Review 6. Baku, Azerb. 2019. p.11. Russian
  4. Probiotiki v kompleksnoj terapii kishechnyh parazitozov u studentov. Mamedova Sh.F. Sağlamlıq jurnalı. 2021;6:159-162. Russian
  5. Guseynova N, Mamedova S. Influence of parasitosis on the immune system of the body and on intestinal disbiosis. Abstracts of the First Eurasian conference «The coronavirus pandemic and critical ict infrastructure». Tbilisi, Georgia. November 28-30, 2020. p. 36. https://doi.org/10.21467/abstracts.102
  6. Guseynova N, Mamedova S. Influence of the intestinal form of COVID-19 and intestinal parasitosis on the body immune state. Abstracts of the Sekond Eurasian Conference «The coronavirus pandemic and critical ict infrastructure». Tbilisi, Georgia, 2021. p. 36.
  7. Miroshnik OA, Red’kin Ju.V. Immunomoduljatory v Rossii (spravochnik). 2006. 428 р. Russian
  8. Rimarchuk GV, Shhepljagina LA., Kruglova IV, Tjurina T.K. Narushenie mikroflory kishechnika. Moskva; 2008. 32 р. Russian