Chilmonchik N. EMosin O.V., Zhigimont A.V., Verkhovodko A.I.

Grodno State Medical University, Grodno, Belarus, Department of Public Health and Public Health Service.

The article presents the history of the creation of the first anti-blastomic agents for the treatment of malignant neoplasms of human lymphoid tissue. The way drugs were invented is analyzed: from a chemical warfare agent to the first clinical trial of cytotoxic substances in humans with, albeit temporary, but pronounced positive effect.

Key Words: antineoplastic chemotherapy, mustard gas, hematological toxicity, lymphoma, clinical trial.

https://dx.doi.org/10.15407/internalmed2020.02.143

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For citing:

1. Хильмончик, Н. Е. Химиотерапевтические противоопухолевые лекарственные препараты. История лечения злокачественных новообразований лимфоидной ткани / Н. Е. Хильмончик, О.В. Мосин, А.В. Жигимонт, А.И. Верховодко // Східноєвропейський журнал внутрішньої та сімейної медицини. – 2020. – № 2. – С. 143-145. doi: 10.15407/internalmed2020.02.143.
2. Chilmonchik NE, Mosin OV, Zhigimont AV, Verkhovodko AI. [Chemotherapeutic antitumor drugs. History of lymphoid tissue malignant treatment]. Shidnoevr. z. vnutr. simejnoi med. 2020;2:143-145. Russian. doi: 10.15407/internalmed2020.02.143.

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