Pathophysiological and biochemical-molecular concepts of the comorbid course of gastroesophageal reflux disease and obesity in young people

Prof. A.G. Oparin, assoc. prof. Yu. G. Fedchenko, assoc. prof. A.V. Blagoveshchenska, assoc. prof. Khomenko, assoc. prof. A.E. Novohatnya, assoc. prof. T.M. Oparina, asp. O.M. Kashirtseva, asst. I.P. Korenovsky Kharkiv National Medical University The article analyzes the latest ideas about the pathogenetic mechanisms of the combined formation of gastroesophageal reflux disease and obesity in young…

The role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflx disease and chronic obstructive pulmonary inflmmation

Prof. O.A. Oparin, PhD. A.V. Blagoveshchenska, PhD. L.O. Khomenko, as. N.V. Semenova, PhD A.E. Novokhatnia, PhD. T.M. Oparina, ass. I.P. Korenovsky Kharkiv National Medical University The paper analyzes the role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflux disease and chronic obstructive pulmonary inflammation. It is shown…

Current concepts about influence of thyroid gland hormones on the development and course of gastro-esophageal reflux disease

Prof. Oparin O.A., prof. Oparin A.G., asst Yarantseva N.А., assoc. prof. Novokhatnya А.E., assoc. prof. Chomenko L.O., asst. Korenovskiy I.P. Kharkiv National Medical University The problem of gastroesophageal reflux disease (GERD) remains one of the most relevant in modern gastroenterology. In recent decades, there has been a tendency to increase in the incidence of GERD…

New approaches in the diagnosis and treatment of non-alcoholic fatty liver disease

Prof. Sergienko O.I., prof. Oparin A.G., assoc. prof. Novokhatnya А.E.   Kharkiv National Medical University Department of therapy №2 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of liver diseases: 25% of the population of European countries have signs of NAFLD, 10–20% of patients with steatosis develop an inflammatory process (non-alcoholic…

Gastroesophageal reflux disease: current insights into pathogenesis, diagnosis and treatment

PhD. Yarantseva N.А., assoc. prof. Oparina T.N., assoc. prof. Novokhatnya А.E. Kharkiv National Medical University Gastroesophageal reflux disease (GERD) affects millions of people worldwide with significant clinical consequences [1, 2]. GERD presents with recurrent and severe heartburn and regurgitation or GERD-specific complications and affects approximately 20% of the adult population in high-income countries [3, 4,…