A.Y. Mehtiyeva
Azerbaijan Medical University, Department of Radiology
Imaging plays a central role in the detection and monitoring of pulmonary involvement in COVID-19
Aim: To assess the clinical significance and follow-up implications of incidental findings detected on computed tomography (CT) and magnetic resonance imaging (MRI) in patients with COVID-19. Materials and Methods: Retrospective analysis of 107 patients (25–71 years). Chest CT examinations were performed using multidetector scanners. A subset of 32 patients underwent additional magnetic resonance imaging examination as part of follow-up assessment
Results: Typical CT findings in 62.6%; incidental findings in 18.7%. MRI follow-up showed significant reduction of lesions (p<0.05, Cohen’s d=0.72). Follow-up CT (n=68 patients) at 3-6 months demonstrated complete resolution in 33 patients (48.5%), residual abnormalities in 26 patients (38.2%) and fibrotic-like changes in 9 patients (13.2%). Patients with initial severe lung involvement were significantly more likely to develop residual abnormalities (OR = 3.12; 95% CI: 1.41-6.89; p = 0.004). Multivariate regression confirmed baseline extent of lung involvement as an independent predictor of residual changes (adjusted OR = 2.87; 95% CI: 1.25-6.54; p = 0.01)
Conclusion: Thus, the integration of CT and MRI findings provides a more comprehensive understanding of disease evolution. CT remains indispensable for acute assessment, while MRI offers a valuable radiation-free alternative for follow-up, particularly in younger or vulnerable populations
Key words: COVID-19, computed tomography, magnetic resonance imaging, follow-up
https://doi.org/10.15407/internalmed2026.01.100
Cite:
Мехтієва, А.Я. Клінічна значимість та подальше спостереження за випадковими знахідками, виявленими при комп’ютерній томографії та магнітно-резонансній діагностиці, для діагностики COVID-19 / А.Я. Мехтієва // Східноєвропейський журнал внутрішньої та сімейної медицини. — 2026. — № 1. — С. 100-103. (English) doi: 10.15407/internalmed2026.01.100
Mehtiyeva AY. Clinical relevance and follow-up of incidental computed tomography imaging and magnetic resonance imaging findings for COVID-19 diagnosis. Shidnoevr. z. vnutr. simejnoi med. 2026;1:100-103. doi: 10.15407/internalmed2026.01.100
References:
-
Cucinotta D, Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020;91(1):157-160. https://doi.org/10.23750/abm.v91i1.9397
-
Ochani R, Asad A, Yasmin F, Shaikh S, Khalid H, Batra S, et al. COVID-19 pandemic: from origins to outcomes. A comprehensive review of viral pathogenesis, clinical manifestations, diagnostic evaluation, and management. Infez Med. 2021;29(1):20-36.
-
Filchakova O, Dossym D, Ilyas A, Kuanysheva T, Abdizhamil A, Bukasov R. Review of COVID-19 testing and diagnostic methods. Talanta. 2022;244:123409. https://doi.org/10.1016/j.talanta.2022.123409
-
Darwish HS, Habash MY, Habash WY. Chest computed tomography imaging features in patients with coronavirus disease 2019 (COVID-19). J Int Med Res. 2021;49(5):3000605211010631. https://doi.org/10.1177/03000605211010631
-
Zhao W, Zhong Z, Xie X, Yu Q, Liu J. Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study. AJR Am J Roentgenol. 2020;214(5):1072-1077. https://doi.org/10.2214/AJR.20.22976
-
Marty M, Kerber B, Abel F, Kroschke J, Frauenfelder T, Franckenberg S. Clinical Relevance and Follow-Up of Incidental CT Imaging Findings for COVID-19 Diagnosis: A Retrospective Analysis. Diagnostics (Basel). 2025;15(22):2832. https://doi.org/10.3390/diagnostics15222832
-
Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020;296(2):E32-E40. https://doi.org/10.1148/radiol.2020200642
-
Kwee TC, Kwee RM. Chest CT in COVID-19: What the Radiologist Needs to Know. Radiographics. 2020;40(7):1848-1865. Erratum in: Radiographics. 2022;42(1):E32. https://doi.org/10.1148/rg.2020200159
-
Sobhanardekani M, Ameri Ahmad Z, Shokrolahi M, Ghasemipour S. MRI Findings in Covid-19 Patients With Lung Involvement Before and After the Treatment: Comparative Study. South East Eur J Public Health. 2024;2024:1587-1595. https://doi.org/10.70135/seejph.vi.2929
-
Yoon SH, Kanne JP, Ashizawa K, Biederer J, Castañer E, Fan L, et al. Best Practice: International Multisociety Consensus Statement for Post-COVID-19 Residual Abnormalities on Chest CT Scans. Radiology. 2025;316(1):e243374. https://doi.org/10.1148/radiol.243374