{"id":3858,"date":"2023-12-17T16:01:27","date_gmt":"2023-12-17T14:01:27","guid":{"rendered":"http:\/\/www.internalmed-journal.in.ua\/?p=3858"},"modified":"2025-06-05T19:10:53","modified_gmt":"2025-06-05T17:10:53","slug":"%d1%85%d0%b2%d0%be%d1%80%d0%be%d0%b1%d0%b0-%d0%bb%d0%b0%d0%b9%d0%bc%d0%b0-%d0%ba%d0%bb%d1%96%d0%bd%d1%96%d1%87%d0%bd%d0%b0-%d0%bb%d0%b5%d0%ba%d1%86%d1%96%d1%8f","status":"publish","type":"post","link":"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/3858","title":{"rendered":"Lyme disease (clinical lecture)"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Assoc. prof. Florikyan V.A., Assoc. prof. Tondiy O.L., Assoc. prof. Zavalna O.P. <\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Educational and Scientific Institute of Postgraduate Education of Kharkiv National Medical University <\/strong><\/p>\n<p style=\"text-align: justify;\">The article is a clinical lecture devoted to an interdisciplinary problem \u2014 Lyme disease (Lyme \u2014 borreliosis). This disease is widespread on the territory of Ukraine, transmitted through a tick bite. Often the diagnosis is untimely, the cause is unknown. This creates numerous difficulties for differential diagnosis and etiotropic treatment.<\/p>\n<p style=\"text-align: justify;\"><strong>Key words:<\/strong> Lyme borreliosis, myofascial pain, neuropathic pain, immunoblotting, etiotropic treatment<\/p>\n<p style=\"text-align: justify;\"><strong> https:\/\/doi.org\/10.15407\/internalmed2023.02b.079<\/strong><\/p>\n<p><a href=\"http:\/\/www.internalmed-journal.in.ua\/wp-content\/uploads\/2024\/06\/\u0416\u0443\u0440\u043d\u0430\u043b_2\u0411_2023_28_01_2024-79-87.pdf\"><strong>Download.PDF<\/strong><\/a><\/p>\n<p style=\"text-align: justify;\"><strong>Cite:<\/strong><\/p>\n<p>\u0424\u043b\u043e\u0440\u0456\u043a\u044f\u043d, \u0412.\u0410. \u0425\u0432\u043e\u0440\u043e\u0431\u0430 \u041b\u0430\u0439\u043c\u0430 (\u043a\u043b\u0456\u043d\u0456\u0447\u043d\u0430 \u043b\u0435\u043a\u0446\u0456\u044f) \/ \u0412.\u0410. \u0424\u043b\u043e\u0440\u0456\u043a\u044f\u043d, \u041e.\u041b. \u0422\u043e\u043d\u0434\u0456\u0439, \u041e.\u041f. \u0417\u0430\u0432\u0430\u043b\u044c\u043d\u0430 \/\/ \u0421\u0445\u0456\u0434\u043d\u043e\u0454\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u044c\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u044c\u043e\u0457 \u0442\u0430 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0457 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0438. &#8211; 2023. &#8211; \u2116 2(\u0411). &#8211; \u0421. 79-87. doi: 10.15407\/internalmed2023.02b.079<\/p>\n<p>Florikyan VA, Tondiy \u041eL, Zavalna OP. [Lyme disease (clinical lecture)]. Shidnoevr. z. vnutr. simejnoi med. 2023;2(B):79-87. Ukrainian. doi: 10.15407\/internalmed2023.02b.079<\/p>\n<p style=\"text-align: justify;\"><strong>References:<\/strong><\/p>\n<ol>\n<li>Holubovska OA, Andreichyna MA, Shkurbata AV. Infektsiini khvoroby, pidruchnyk. Kyiv: VSV \u00abMedytsyna\u00bb (2 vydannia, dopovnene i pereroblene). 2018.688 \u0440. + 12 s. kolor. vkl. P 449-458. Ukrainian<\/li>\n<li>Andreichyn MA. Laim-borelioz. Diahnostychni kryterii, likuvannia i profilaktyka: metod. rekom. Ternopil: TDMU: s Ukrmedknyha; 2019. 52 \u0440. Ukrainian<\/li>\n<li>FDA clears new indications for existing Lyme disease tests that may help streamline diagnoses. U.S. Food &amp; DrugAdministration. Available at https:\/\/www.fda.gov\/newsevents\/press-announcements\/fda-clears-new-indicationsexisting-lyme-disease-tests-may-help-streamline-diagnoses. July 29, 2019; Accessed: April 5, 2021.<\/li>\n<li>Wormser GP, Brisson D, Liveris D, et al. Borrelia burgdorferi genotype predicts the capacity for hematogenous disseminationduring early Lyme disease. J Infect Dis. 2008 Nov 1. 198(9):1358-64. https:\/\/doi.org\/10.1086\/592279<\/li>\n<\/ol>\n<ol start=\"5\">\n<li>Centers for Disease Control and Prevention. Lyme Disease: Data and Surveillance. CDC. Available. thttp:\/\/www.cdc.gov\/lyme\/stats\/index.html?s_cid=cs_281. January 14, 2021; Accessed: March 30, 2021<\/li>\n<li>Dandache P, Nadelman RB. Erythema migrans. Infect Dis Clin North Am. 2008 Jun. 22(2):235-60, vi. https:\/\/doi.org\/10.1016\/j.idc.2007.12.012<\/li>\n<\/ol>\n<ol start=\"7\">\n<li>Tibbles CD, Edlow JA. Does this patient have erythema migrans?. JAMA. 2007 Jun 20. 297(23):2617-27. https:\/\/doi.org\/10.1001\/jama.297.23.2617<\/li>\n<\/ol>\n<ol start=\"8\">\n<li>Nigrovic LE, Thompson AD, Fine AM, Kimia A. Clinical predictors of Lyme disease among children with a peripheral facial palsyat an emergency department in a Lyme diseaseendemic area. Pediatrics. 2008 Nov. 122(5):e1080-5. https:\/\/doi.org\/10.1542\/peds.2008-1273<\/li>\n<\/ol>\n<ol start=\"9\">\n<li>Steere AC. Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses. J Clin Invest.2020 May 1. 130 (5):2148-2151. https:\/\/doi.org\/10.1172\/JCI138062<\/li>\n<\/ol>\n<ol start=\"10\">\n<li>Shah A, O&#8217;Horo JC, Wilson JW, Granger D, Theel ES. An Unusual Cluster of Neuroinvasive Lyme Disease Cases PresentingWith Bannwarth Syndrome in the Midwest United States. Open Forum Infect Dis. 2017. 5:1-3. https:\/\/doi.org\/10.1093\/ofid\/ofx276<\/li>\n<\/ol>\n<ol start=\"11\">\n<li>Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT. Toll-like receptors: insights into their possible role in thepathogenesis of lyme neuroborreliosis. Infect Immun. 2008 Oct. 76(10):4385-95. https:\/\/doi.org\/10.1128\/IAI.00394-08<\/li>\n<\/ol>\n<ol start=\"12\">\n<li>Stanek G, Strle F. Lyme disease: European perspective. Infect Dis Clin North Am. 2008 Jun. 22(2):327-39, vii. https:\/\/doi.org\/10.1016\/j.idc.2008.01.001<\/li>\n<\/ol>\n<ol start=\"13\">\n<li>John O Meyerhoff, MD; Chief Editor: Herbert S Diamond, MD, Medscape, 05 Apr 2021.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Assoc. prof. Florikyan V.A., Assoc. prof. Tondiy O.L., Assoc. prof. Zavalna O.P. Educational and Scientific Institute of Postgraduate Education of Kharkiv National Medical University The article is a clinical lecture devoted to an interdisciplinary problem \u2014 Lyme disease (Lyme \u2014 borreliosis). This disease is widespread on the territory of Ukraine, transmitted through a tick bite&#8230;.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[48,12,43,126],"tags":[],"translation":{"provider":"WPGlobus","version":"2.12.2","language":"en","enabled_languages":["uk","en","ru"],"languages":{"uk":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false},"ru":{"title":false,"content":false,"excerpt":false}}},"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3858"}],"collection":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/comments?post=3858"}],"version-history":[{"count":6,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3858\/revisions"}],"predecessor-version":[{"id":4453,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3858\/revisions\/4453"}],"wp:attachment":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/media?parent=3858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/categories?post=3858"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/tags?post=3858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}