{"id":3589,"date":"2023-06-15T23:08:44","date_gmt":"2023-06-15T21:08:44","guid":{"rendered":"http:\/\/www.internalmed-journal.in.ua\/?p=3589"},"modified":"2023-08-11T14:21:00","modified_gmt":"2023-08-11T12:21:00","slug":"%d1%85%d1%80%d0%be%d0%bd%d1%96%d1%87%d0%bd%d0%b0-%d1%81%d0%b5%d1%80%d1%86%d0%b5%d0%b2%d0%b0-%d0%bd%d0%b5%d0%b4%d0%be%d1%81%d1%82%d0%b0%d1%82%d0%bd%d1%96%d1%81%d1%82%d1%8c-%d1%82%d0%b0-%d0%be%d1%81","status":"publish","type":"post","link":"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/3589","title":{"rendered":"Chronic heart failure and osteoporosis: etiological and clinicalpathogenetic relationships"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Prof<\/strong><strong>. <\/strong><strong>Korzh<\/strong> <strong>O<\/strong><strong>.<\/strong><strong>M<\/strong><strong>., <\/strong><strong>PHD<\/strong> <strong>Korzh<\/strong> <strong>I<\/strong><strong>.<\/strong><strong>V<\/strong><strong>.<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Kharkiv National Medical University <\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Sytenko Institute of Spine and Joint Pathology of National Academy of Medical Sciences of Ukraine <\/strong><\/p>\n<p style=\"text-align: justify;\">Current epidemiological and clinical data confirm the relationship between chronic heart failure (CHF) and osteoporosis (OP), which cannot be explained only by aging and the use of pharmacological drugs. Clinical and epidemiological studies show that CHF is most often accompanied by low bone mineral density, a high risk of fractures and, moreover, a fourfold increase in the risk of any fracture requiring hospitalization. Further research on the relationship between CHF and OP is needed, as understanding the common mechanisms of disease development will serve as a platform for preventive and therapeutic interventions aimed at both conditions.<\/p>\n<p style=\"text-align: justify;\"><strong>Key words:<\/strong> chronic heart failure, osteoporosis, bone mineral density, bone metabolism.<\/p>\n<p style=\"text-align: justify;\"><strong>\u00a0<\/strong><a href=\"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/3589\"><strong>https:\/\/doi.org\/10.15407\/internalmed2023.02.084<\/strong><\/a><\/p>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/www.internalmed-journal.in.ua\/wp-content\/uploads\/2023\/06\/\u0416\u0443\u0440\u043d\u0430\u043b_2_2023_19_06-84-89.pdf\"><strong>Download.PDF (ukr)<\/strong><\/a><\/p>\n<p style=\"text-align: justify;\"><strong>Cite:<\/strong><\/p>\n<ol>\n<li>\u041a\u043e\u0440\u0436, \u041e.\u041c. \u0425\u0440\u043e\u043d\u0456\u0447\u043d\u0430 \u0441\u0435\u0440\u0446\u0435\u0432\u0430 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043d\u0456\u0441\u0442\u044c \u0442\u0430 \u043e\u0441\u0442\u0435\u043e\u043f\u043e\u0440\u043e\u0437: \u0435\u0442\u0456\u043e\u043b\u043e\u0433\u0456\u0447\u043d\u0456 \u0442\u0430 \u043a\u043b\u0456\u043d\u0456\u043a\u043e\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0442\u0438\u0447\u043d\u0456 \u0432\u0437\u0430\u0454\u043c\u043e\u0437\u0432\u2019\u044f\u0437\u043a\u0438 \/ \u041e.\u041c. \u041a\u043e\u0440\u0436, \u0406.\u0412. \u041a\u043e\u0440\u0436 \/\/ \u0421\u0445\u0456\u0434\u043d\u043e\u0454\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u044c\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u044c\u043e\u0457 \u0442\u0430 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0457 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0438. &#8211; 2023. &#8211; \u2116 2. &#8211; \u0421. 84-89. http:\/\/doi.org\/10.15407\/internalmed2023.02.084<\/li>\n<li>Korzh OM, Korzh IV. [Chronic heart failure and osteoporosis: etiological and clinicalpathogenetic relationships]. Shidnoevr. z. vnutr. simejnoi med. 2023;2:84-89. Ukrainian. http:\/\/doi.org\/10.15407\/internalmed2023.02.084<\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><strong>References:<\/strong><\/p>\n<ol>\n<li>Groenewegen A, Rutten FH, Mosterd A. Epidemiology of heart failure. Eur J Heart Fail. 2020;22(8):1342-56. doi:10.1002\/ ejhf.1858.<\/li>\n<li>Virani SS, Alonso A, Benjamin E, American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Committee et al. Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics -2020 update: A report from the American Heart Association. Circulation. 2020;141:e139\u2013596. doi: 10.1161\/CIR.0000000000000757.<\/li>\n<li>GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. 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Elevated levels of the mediator of catabolic bone remodeling RANKL in the bone marrow environment link chronic heart failure with osteoporosis. Circ Heart Fail. 2012;5(6):769-77. doi:10.1161\/ CIRCHEARTFAILURE.111.966093.<\/li>\n<li>Farhat GN, Cauley JA. The link between osteoporosis and cardiovascular disease. Clin Cases Miner Bone Metab. 2008;5(1): 19-34.<\/li>\n<li>Gaudio A, Xourafa A, Rapisarda R. Peripheral artery disease and osteoporosis: Not only agerelated. Mol Med Rep. 2018;18(6):4787-92. doi:10.3892\/mmr.2018.9512.<\/li>\n<li>Katano S, Yano T, Tsukada T. Clinical determinants and prognostic impact of osteoporosis in patients with chronic heart failure. Eur Heart J. 2020;41(2):3418. doi:10.1093\/ehjci\/ ehaa946.3418.<\/li>\n<li>Aluoch AO, Jessee R, Habal H. Heart failure as a risk factor for osteoporosis and fractures. Curr Osteoporos Rep. 2012;10(4):258-69. doi:10.1007\/s11914-012-0115-2.<\/li>\n<li>Gage BF, Birman-Deych E, Radford MJ. Risk of Osteoporotic Fracture in Elderly Patients Taking Warfarin: Results from the National Registry of Atrial Fibrillation 2. Arch Intern Med. 2006;166(2):241-6. doi:10.1001\/ archinte.166.2.241<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Korzh O.M., PHD Korzh I.V. Kharkiv National Medical University Sytenko Institute of Spine and Joint Pathology of National Academy of Medical Sciences of Ukraine Current epidemiological and clinical data confirm the relationship between chronic heart failure (CHF) and osteoporosis (OP), which cannot be explained only by aging and the use of pharmacological drugs. Clinical&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58,9,10,108,117,106],"tags":[],"translation":{"provider":"WPGlobus","version":"2.12.2","language":"en","enabled_languages":["uk","en","ru"],"languages":{"uk":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false},"ru":{"title":false,"content":false,"excerpt":false}}},"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3589"}],"collection":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/comments?post=3589"}],"version-history":[{"count":6,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3589\/revisions"}],"predecessor-version":[{"id":3747,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/3589\/revisions\/3747"}],"wp:attachment":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/media?parent=3589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/categories?post=3589"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/tags?post=3589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}