{"id":2351,"date":"2021-03-11T15:30:53","date_gmt":"2021-03-11T13:30:53","guid":{"rendered":"http:\/\/www.internalmed-journal.in.ua\/?p=2351"},"modified":"2021-11-16T15:27:00","modified_gmt":"2021-11-16T13:27:00","slug":"%d0%b2%d0%b8%d1%80%d0%b0%d0%b6%d0%b5%d0%bd%d1%96%d1%81%d1%82%d1%8c-%d0%ba%d0%bb%d1%96%d0%bd%d1%96%d1%87%d0%bd%d0%b8%d1%85-%d0%bf%d1%80%d0%be%d1%8f%d0%b2%d1%96%d0%b2-%d1%96-%d0%b7%d0%bd%d0%b0%d1%87","status":"publish","type":"post","link":"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/2351","title":{"rendered":"The severity of clinical changes and the importance of vitamin D in the development of hyperandrogenism syndrome during puberty."},"content":{"rendered":"<p><strong>Talibli A.A., Aliyeva E.M., Kurbanova F.A., Mustafayeva I.R., Ismayilova A.C., Amiraslanova Sh.Z <\/strong><\/p>\n<p><strong>Azerbaijan Medical University Department of Obstetrics and Gynecology \u21161 <\/strong><\/p>\n<p>The aim of the study was to study the severity of subjective and clinical manifestations, as well as the peculiarities of changes in the level of vitamin D in girls with hyperandrogenic syndrome in the dynamics of puberty. Examined 137 girls with hypenrandrogenic syndrome (HA) in the period of puberty. Clinical, hormonal, biochemical, X-ray research methods were carried out. All surveyed girls were divided by age into 3 groups: 12-13, 14-15, 16-17 years old. The first group (12-13 years old, n = 27) comprised 19.7% of girls, the second group (14-15 years old, n = 63) 46% girls, the third group (16-17 years old, n = 47) made up 34,7% of girls. The level of vitamin D was determined on a device \u201cFinecare\u201d.<\/p>\n<p><strong>Key Words<\/strong>: Hyperandrogenism, puberty, polycystic ovary syndrome, hyperprolactinemia, vitamin D deficiency.<\/p>\n<p><a href=\"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/2351\"><strong>https<\/strong><strong>:\/\/<\/strong><strong>dx<\/strong><strong>.<\/strong><strong>doi<\/strong><strong>.<\/strong><strong>org<\/strong><strong>\/10.15407\/internalmed2021.01.088<\/strong><\/a><\/p>\n<p><a href=\"http:\/\/www.internalmed-journal.in.ua\/wp-content\/uploads\/2021\/04\/\u0416\u0443\u0440\u043d\u0430\u043b_1_2021_88-92.pdf\"><strong>Download<\/strong><strong>.<\/strong><strong>PDF (rus)<\/strong><\/a><\/p>\n<p><strong>Cite:<\/strong><\/p>\n<p>1. \u0422\u0430\u043b\u044b\u0431\u043b\u044b, \u0410.\u0410., \u0410\u043b\u0438\u0435\u0432\u0430, \u042d.\u041c., \u0413\u0443\u0440\u0431\u0430\u043d\u043e\u0432\u0430, \u0424.\u0410., \u041c\u0443\u0441\u0442\u0430\u0444\u0430\u0435\u0432\u0430, \u0418.\u0420., \u0418\u0441\u043c\u0430\u0439\u043b\u043e\u0432\u0430, \u0410.\u0414\u0436., \u0410\u043c\u0438\u0440\u0430\u0441\u043b\u0430\u043d\u043e\u0432\u0430, \u0428.\u0417. \u0412\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0439 \u0438 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u0432\u0438\u0442\u0430\u043c\u0438\u043d\u0430 \u0414 \u0432 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0438 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0430 \u0433\u0438\u043f\u0435\u0440\u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d\u0438\u0438 \u0432 \u043f\u0435\u0440\u0438\u043e\u0434\u0435 \u043f\u043e\u043b\u043e\u0432\u043e\u0433\u043e \u0441\u043e\u0437\u0440\u0435\u0432\u0430\u043d\u0438\u044f \/\/ \u0421\u0445\u0456\u0434\u043d\u043e\u0454\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u044c\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u044c\u043e\u0457 \u0442\u0430 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0457 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0438. &#8211; 2021. &#8211; \u21161. \u2013 \u0421. 88-92. doi: 10.15407\/internalmed2021.01.088<\/p>\n<p>2. Talibli A\u0410, Aliyeva EM, Kurbanova FA, Mustafayeva IR, Ismayilova AC, Amiraslanova ShZ [The severity of clinical changes and the importance of vitamin D in the development of hyperandrogenism syndrome during puberty]. Shidnoevr. z. vnutr. simejnoi med. 2021;1:88-92. Russian. doi: 10.15407\/internalmed2021.01.088<\/p>\n<p><strong>References<\/strong><strong>:<\/strong><\/p>\n<p>1. Spirichev VB, Gromova OA. Vitamin D i ego sinergienty. Zh. \u00abZemskij Vrach\u00bb. 2012;2 vyp.13:33-38. Russian<\/p>\n<p>2. Al-Daghri N, Al-Attas O, Alkharfy K, Khan N, Mohammed A, Vinodson B, Ansari M, Alenad A, Alokail M. Association of VDR-gene variants with factors related to the metabolic syndrome, type 2 diabetes and vitamin D deficiency. Gene. 2014;542(2):129-133. http:\/\/dx.doi.org\/10.1016\/j.gene.2014.03.044<br \/>\nhttps:\/\/doi.org\/10.1016\/j.gene.2014.03.044<\/p>\n<p>3. Anagnostis P, Karras S, Goulis D. Vitamin D in human reproduction: a narrative review. 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International Journal of Obesity. 2013;38(1):46-52. http:\/\/dx.doi.org\/10.1038\/ijo.2013.75<br \/>\nhttps:\/\/doi.org\/10.1038\/ijo.2013.75<\/p>\n<p>16. Stewart N, Lewis S. Vitamin D deficiency in adolescents in a tier 4 psychiatric unit. BJPsych Bulletin. 2017;41(3):133-136. http:\/\/dx.doi.org\/10.1192\/pb.bp.115.053298<br \/>\nhttps:\/\/doi.org\/10.1192\/pb.bp.115.053298<\/p>\n<p>17. Thomson R, Spedding S, Brinkworth G, Noakes M, Buckley J. Seasonal effects on vitamin D status influence outcomes of lifestyle intervention in overweight and obese women with polycystic ovary syndrome. Fertility and Sterility. 2013;99(6):1779-1785. http:\/\/dx.doi.org\/10.1016\/j.fertnstert.2012.12.042<br \/>\nhttps:\/\/doi.org\/10.1016\/j.fertnstert.2012.12.042<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Talibli A.A., Aliyeva E.M., Kurbanova F.A., Mustafayeva I.R., Ismayilova A.C., Amiraslanova Sh.Z Azerbaijan Medical University Department of Obstetrics and Gynecology \u21161 The aim of the study was to study the severity of subjective and clinical manifestations, as well as the peculiarities of changes in the level of vitamin D in girls with hyperandrogenic syndrome in&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39,17,43,54],"tags":[],"translation":{"provider":"WPGlobus","version":"2.12.2","language":"en","enabled_languages":["uk","en","ru"],"languages":{"uk":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false},"ru":{"title":true,"content":true,"excerpt":false}}},"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2351"}],"collection":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/comments?post=2351"}],"version-history":[{"count":4,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2351\/revisions"}],"predecessor-version":[{"id":2965,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2351\/revisions\/2965"}],"wp:attachment":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/media?parent=2351"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/categories?post=2351"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/tags?post=2351"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}