{"id":2317,"date":"2021-03-11T14:49:44","date_gmt":"2021-03-11T12:49:44","guid":{"rendered":"http:\/\/www.internalmed-journal.in.ua\/?p=2317"},"modified":"2021-11-16T15:10:29","modified_gmt":"2021-11-16T13:10:29","slug":"helicobacter-pylori-%d0%b2-%d0%ba%d0%bb%d1%96%d0%bd%d1%96%d1%86%d1%96-%d0%b2%d0%bd%d1%83%d1%82%d1%80%d1%96%d1%88%d0%bd%d1%96%d1%85-%d1%85%d0%b2%d0%be%d1%80%d0%be%d0%b1","status":"publish","type":"post","link":"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/2317","title":{"rendered":"Helicobacter pylori in the clinic of internal medicine"},"content":{"rendered":"<p><strong>Prof. T.D. Zvyagintseva, as. Ya. K. Gamanenko <\/strong><\/p>\n<p><strong>Kharkiv medical academy of postgraduation education <\/strong><\/p>\n<p>The article is devoted to the analysis of the literature on the problem of the possible relationship of Helicobacter pylori in the pathogenesis of various extragastric pathologies &#8211; diabetes mellitus, metabolic syndrome, cardiovascular diseases and multiple sclerosis. It is possible that Helicobacter pylori infection plays an independent role in the pathogenesis of these diseases.<\/p>\n<p><strong>Key words<\/strong>: Helicobacter pylori infection, type 2 diabetes mellitus, insulin resistance, glycated hemoglobin, metabolic syndrome, dyslipidemia.<\/p>\n<p><a href=\"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/2317\"><strong>\u00a0<\/strong><strong>https<\/strong><strong>:\/\/<\/strong><strong>dx<\/strong><strong>.<\/strong><strong>doi<\/strong><strong>.<\/strong><strong>org<\/strong><strong>\/10.15407\/internalmed2021.01.017<\/strong><\/a><\/p>\n<p><a href=\"http:\/\/www.internalmed-journal.in.ua\/wp-content\/uploads\/2021\/04\/\u0416\u0443\u0440\u043d\u0430\u043b_1_2021_17-21.pdf\" target=\"_blank\" rel=\"noopener\"><strong>Download<\/strong><strong>.<\/strong><strong>PDF (ukr)<\/strong><\/a><\/p>\n<p><strong>For citing:<\/strong><\/p>\n<p>1. \u0417\u0432\u044f\u0433\u0438\u043d\u0446\u0435\u0432\u0430, \u0422.\u0414., \u0413\u0430\u043c\u0430\u043d\u0435\u043d\u043a\u043e, \u042f.\u041a. Helicobacter pylori \u0432 \u043a\u043b\u0456\u043d\u0456\u0446\u0456 \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u0456\u0445 \u0445\u0432\u043e\u0440\u043e\u0431 \/\/ \u0421\u0445\u0456\u0434\u043d\u043e\u0454\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u044c\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u044c\u043e\u0457 \u0442\u0430 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0457 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0438. &#8211; 2021. &#8211; \u21161. \u2013 \u0421. 17-21. doi: 10.15407\/internalmed2021.01.017<\/p>\n<p>2. Zvyagintseva TD, Gamanenko YaK. [Helicobacter pylori in the clinic of internal medicine]. Shidnoevr. z. vnutr. simejnoi med. 2021;1:17-21. Ukrainian. doi: 10.15407\/internalmed2021.01.017<\/p>\n<p><strong>References:<\/strong><\/p>\n<p>1. Albaker WI. Helicobacter pylori infection and its relationship to metabolic syndrome. Is it myth or fact? Saudi J Gastroenterol. 2011;17(3):165-169. https:\/\/doi.org\/10.4103\/1319-3767.80377<br \/>\nhttps:\/\/doi.org\/10.4103\/1319-3767.80377<\/p>\n<p>2. Lazebnik LB, Zvenigorodskaja LA. Metabolicheskij sindrom i organy pishhevarenija. Moscow: Anaharsis; 2014. 184 \u0440. Russian<\/p>\n<p>3. Giudice A, Crispo A, Massimiliano G, D&#8217;Arena G, Tecce MF, Grimaldi M, Amore A, Esposito E, Montella M. Metabolic syndrome, insulin resistance, circadian disruption, antioxidants and pancreatic carcinoma: an overview. J Gastrointestin Liver Dis. 2014 Mar;23(1):73-7. PMID: 24689100.<br \/>\nhttps:\/\/doi.org\/10.15403\/jgld-1282<\/p>\n<p>4. Hoffman EL, VonWald T, Hansen K. The metabolic syndrome. S D Med. 2015;Spec No:24-8. PMID: 25985604.<\/p>\n<p>5. Bajaj S, Rekwal L, Misra SP, Misra V, Yadav RK, Srivastava A. Association of Helicobacter pylori infection with type 2 diabetes. Indian J Endocrinol Metab. 2018;18:694-699.<\/p>\n<p>6. Dai Y-N, Yu W-L, Zhu H-T, Ding J-X, Yu C-H, Li Y-M. Is Helicobacter pylori infection associated with glycemic control in diabetes? WJG. 2019;21(17):5407-5416.<br \/>\nhttps:\/\/doi.org\/10.3748\/wjg.v21.i17.5407<\/p>\n<p>7. Evans J, Maddux B, Goldfine I. The Molecular Basis for Oxidative Stress-Induced Insulin Resistance. Antioxidants &amp; Redox Signaling. 2005;7(7-8):1040-1052. http:\/\/dx.doi.org\/10.1089\/ars.2005.7.1040<br \/>\nhttps:\/\/doi.org\/10.1089\/ars.2005.7.1040<\/p>\n<p>8. Erdogan A, Asma S, Gereklioglu C, Turan I, Abaci K. Significant Association Between Helicobacter Pylori Infection and Low Density Lipoprotein Cholesterol. Turkish Journal of Family Medicine &amp; Primary Care. 2014;8(1):19. http:\/\/dx.doi.org\/10.5455\/tjfmpc.41121<br \/>\nhttps:\/\/doi.org\/10.5455\/tjfmpc.41121<\/p>\n<p>9. Gayoso-Diz P, Otero-Gonz\u00e1lez A, Rodriguez-Alvarez M, Gude F, Garc\u00eda F, De Francisco A, Quintela A. Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocrine Disorders. 2013;13(1):. http:\/\/dx.doi.org\/10.1186\/1472-6823-13-47<br \/>\nhttps:\/\/doi.org\/10.1186\/1472-6823-13-47<\/p>\n<p>10. Koklu H, Koklu S, Cinar H. Helicobacter pylori and metabolic syndrome. The Turkish Journal of Gastroenterology. 2016;27(2):201-201. http:\/\/dx.doi.org\/10.5152\/tjg.2015.150509<br \/>\nhttps:\/\/doi.org\/10.5152\/tjg.2015.150509<\/p>\n<p>11. Kop\u00e1\u010dov\u00e1 M, Bure\u0161 J, Koupil I, Rejchrt S, Vo\u0159\u00ed\u0161ek V, Seifert B, Pozler O, \u017divn\u00fd P, Douda T, Pali\u010dka V, Hol\u010d\u00edk J. Body indices and basic vital signs in Helicobacter pylori positive and negative persons. European Journal of Epidemiology. 2006;22(1):67-75. http:\/\/dx.doi.org\/10.1007\/s10654-006-9090-1<br \/>\nhttps:\/\/doi.org\/10.1007\/s10654-006-9090-1<\/p>\n<p>12. Malfertheiner P, Megraud F, O&#8217;Morain C. Management of Helicobacter pylori infection &#8211; Maastricht V Florence Consensus Report. 2017;47:324-331.<\/p>\n<p>13. Nam S, Ryu K, Park B, Park S. Effects ofHelicobacter pyloriInfection and Its Eradication on Lipid Profiles and Cardiovascular Diseases. Helicobacter. 2014;20(2):125-132. http:\/\/dx.doi.org\/10.1111\/hel.12182<br \/>\nhttps:\/\/doi.org\/10.1111\/hel.12182<\/p>\n<p>14. Lu L, Hao N, Liu J, Li X, Wang R. Correlation between Helicobacter pylori Infection and Metabolic Abnormality in General Population: A Cross-Sectional Study. Gastroenterology Research and Practice. 2018;2018:1-6. http:\/\/dx.doi.org\/10.1155\/2018\/7410801<br \/>\nhttps:\/\/doi.org\/10.1155\/2018\/7410801<\/p>\n<p>15. Henriksen E, Diamond-Stanic M, Marchionne E. Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radical Biology and Medicine. 2011;51(5):993-999. http:\/\/dx.doi.org\/10.1016\/j.freeradbiomed.2010.12.005<br \/>\nhttps:\/\/doi.org\/10.1016\/j.freeradbiomed.2010.12.005<\/p>\n<p>16. Roper J, Francois F, Shue P, Mourad M, Pei Z, Olivares de Perez A, Perez-Perez G, Tseng C, Blaser M. Leptin and Ghrelin in Relation to Helicobacter pylori Status in Adult Males. The Journal of Clinical Endocrinology &amp; Metabolism. 2008;93(6):2350-2357. http:\/\/dx.doi.org\/10.1210\/jc.2007-2057<br \/>\nhttps:\/\/doi.org\/10.1210\/jc.2007-2057<\/p>\n<p>17. Ramadan A. Impact of cytotoxin-associated gene of Helicobacter pylori strains on microalbuminuria in type 2 diabetes. Saud J Kidney Dis Transpl. 2016;21(4):694-700.<\/p>\n<p>18. Sugano K, Tack J, Kuipers E, Graham D, El-Omar E, Miura S, Haruma K, Asaka M, Uemura N, Malfertheiner P. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9):1353-1367. http:\/\/dx.doi.org\/10.1136\/gutjnl-2015-309252<br \/>\nhttps:\/\/doi.org\/10.1136\/gutjnl-2015-309252<\/p>\n<p>19. Spranger J, Kroke A, Mohlig M, Hoffmann K, Bergmann M, Ristow M, Boeing H, Pfeiffer A. Inflammatory Cytokines and the Risk to Develop Type 2 Diabetes: Results of the Prospective Population-Based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes. 2003;52(3):812-817. http:\/\/dx.doi.org\/10.2337\/diabetes.52.3.812<br \/>\nhttps:\/\/doi.org\/10.2337\/diabetes.52.3.812<\/p>\n<p>20. Yang G, Wu J, Yang Y, Huang Y, Lu F, Chang C. Gastric Helicobacter pylori infection associated with risk of diabetes mellitus, but not prediabetes. Journal of Gastroenterology and Hepatology. 2014;29(10):1794-1799. http:\/\/dx.doi.org\/10.1111\/jgh.12617<br \/>\nhttps:\/\/doi.org\/10.1111\/jgh.12617<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. T.D. Zvyagintseva, as. Ya. K. Gamanenko Kharkiv medical academy of postgraduation education The article is devoted to the analysis of the literature on the problem of the possible relationship of Helicobacter pylori in the pathogenesis of various extragastric pathologies &#8211; diabetes mellitus, metabolic syndrome, cardiovascular diseases and multiple sclerosis. It is possible that Helicobacter&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,48,54],"tags":[],"translation":{"provider":"WPGlobus","version":"2.12.2","language":"en","enabled_languages":["uk","en","ru"],"languages":{"uk":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false},"ru":{"title":true,"content":true,"excerpt":false}}},"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2317"}],"collection":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/comments?post=2317"}],"version-history":[{"count":5,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2317\/revisions"}],"predecessor-version":[{"id":2951,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/2317\/revisions\/2951"}],"wp:attachment":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/media?parent=2317"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/categories?post=2317"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/tags?post=2317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}