{"id":1863,"date":"2020-03-14T22:31:07","date_gmt":"2020-03-14T19:31:07","guid":{"rendered":"http:\/\/www.internalmed-journal.in.ua\/?p=1863"},"modified":"2021-07-29T23:58:15","modified_gmt":"2021-07-29T21:58:15","slug":"%d0%b0%d1%83%d1%82%d0%be%d0%b8%d0%bc%d1%83%d0%bd%d0%bd%d0%b8%d0%b9-%d1%82%d0%b8%d1%80%d0%b5%d0%be%d0%b8%d0%b4%d0%b8%d1%82-%d0%b2%d0%b7%d0%b3%d0%bb%d1%8f%d0%b4-%d0%bd%d0%b0-%d0%bf%d1%80%d0%be%d0%b1","status":"publish","type":"post","link":"http:\/\/www.internalmed-journal.in.ua\/en\/archives\/1863","title":{"rendered":"Autoimmune thyroiditis: a look at the problem through the eyes of a family doctor"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><em>E.Ya Nikolenko., O.A. Salun, K.V.Vovk, E.L.Pavlova<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\"><strong><em>N. Karazin Kharkiv National University<\/em><\/strong><strong><em>, <\/em><\/strong><strong><em>Department of General Practice-Family Medicine<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">This article is about autoimmune thyroid disease, the causes of this pathology, factors of development of AIT. Recent studies have shown that gene mutations, including regulatory genes, cause the development of thyroid, including AIT, so far there is no doubt that AIT is a genetically conditioned disease and also depends on the environment. Analysis of the literature has shown that the information on the real incidence of AIT is rather sparse and controversial. Talking about the exact prevalence of AIT itself is not possible, since the independent clinical problem in modern foreign scientific literature is hardly discussed. AIT statistics are increasing every year. AIT requires further study and development of early diagnosis of the disease.<\/p>\n<p style=\"text-align: justify;\"><strong>\u041a<\/strong><strong>ey Words: <\/strong>autoimmune thyroid disease, diagnosis.<\/p>\n<p style=\"text-align: justify;\">https:\/\/dx.doi.org\/10.15407\/internalmed2020.01.092<\/p>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/www.internalmed-journal.in.ua\/wp-content\/uploads\/2021\/07\/\u0416\u0443\u0440\u043d\u0430\u043b_1_2020-2-92-94.pdf\" target=\"_blank\">Download.PDF(ukr)<\/a><\/p>\n<p style=\"text-align: justify;\"><strong>For citing:<\/strong><\/p>\n<p style=\"text-align: justify;\">1.\u00a0\u041d\u0456\u043a\u043e\u043b\u0435\u043d\u043a\u043e, \u0404.\u042f. \u0410\u0443\u0442\u043e\u0456\u043c\u0443\u043d\u043d\u0438\u0439 \u0442\u0438\u0440\u0435\u043e\u0457\u0434\u0438\u0442: \u043f\u043e\u0433\u043b\u044f\u0434 \u043d\u0430 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u0443 \u043e\u0447\u0430\u043c\u0438 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0433\u043e \u043b\u0456\u043a\u0430\u0440\u044f \/ \u0404.\u042f. \u041d\u0456\u043a\u043e\u043b\u0435\u043d\u043a\u043e, \u041e.\u041e. \u0421\u0430\u043b\u0443\u043d, \u041a.\u0412. \u0412\u043e\u0432\u043a, \u041e.\u041b. \u041f\u0430\u0432\u043b\u043e\u0432\u0430 \/\/ \u0421\u0445\u0456\u0434\u043d\u043e\u0454\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u044c\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b \u0432\u043d\u0443\u0442\u0440\u0456\u0448\u043d\u044c\u043e\u0457 \u0442\u0430 \u0441\u0456\u043c\u0435\u0439\u043d\u043e\u0457 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0438. &#8211; 2020. &#8211; \u2116 1. &#8211; \u0421. 92-94. doi: 10.15407\/internalmed2020.01.092<\/p>\n<p style=\"text-align: justify;\">2. Nikolenko EYa, Salun OA, Vovk KV, Pavlova EL. [Autoimmune thyroiditis: a look at the problem through the eyes of a family doctor]. Shidnoevr. z. vnutr. simejnoi med. 2020;1:92-94. doi: 10.15407\/internalmed2020.01.092. Ukrainian.<\/p>\n<p style=\"text-align: justify;\"><strong>References:<\/strong><\/p>\n<p style=\"text-align: justify;\">1. Swain M, Swain T, Mohanty B. Autoimmune thyroid disorders-An update. Indian Journal of Clinical Biochemistry. 2005;20(1):9-17. http:\/\/dx.doi.org\/10.1007\/bf02893034<br \/>\nhttps:\/\/doi.org\/10.1007\/BF02893034<\/p>\n<p>2. Sheremet MI, Shidlovskyi VO, Sydorchuk LP. Avtoimunnyi tyreoidyt. Suchasni pohliady na patohenez ta likuvannia. Endokrynologia. 2014;19(3):227-228. Ukrainian. ISSN 1680-1466<\/p>\n<p>3. Negro R. Levothyroxine before conception in women with thyroid antibodies: a step forward in the management of thyroid disease in pregnancy. Thyroid Research. 2019;12(1):5. https:\/\/doi.org\/10.1186\/ s13044-019-0066-0<br \/>\nhttps:\/\/doi.org\/10.1186\/s13044-019-0066-0<\/p>\n<p>4. Chervonsky A. Influence of microbial environment on autoimmunity. Nature Immunology. 2009;11(1):28-35. http:\/\/dx.doi.org\/10.1038\/ni.1801<br \/>\nhttps:\/\/doi.org\/10.1038\/ni.1801<\/p>\n<p>5. Kondrashova A, Seiskari T, Ilonen J, Knip M, Hy\u00f6ty H. The &#8216;Hygiene hypothesis&#8217; and the sharp gradient in the incidence of autoimmune and allergic diseases between Russian Karelia and Finland. APMIS. 2012;121(6):478-493. http:\/\/dx.doi.org\/10.1111\/apm.12023<br \/>\nhttps:\/\/doi.org\/10.1111\/apm.12023<\/p>\n<p>6. Vitti P, Aghini-Lombardi F. The effect of 15 years voluntary iodine prophylaxis through iodized salt in a small rural community: The Pescopagano experience. Annales d&#8217;Endocrinologie. 2011;72(2):162-163. http:\/\/dx.doi.org\/10.1016\/j.ando.2011.03.022<br \/>\nhttps:\/\/doi.org\/10.1016\/j.ando.2011.03.022<\/p>\n<p>7. van Zuuren E, Albusta A, Fedorowicz Z, Carter B, Pijl H. Selenium Supplementation for Hashimoto&#8217;s Thyroiditis: Summary of a Cochrane Systematic Review. European Thyroid Journal. 2013;3(1):25-31. http:\/\/dx.doi.org\/10.1159\/000356040<br \/>\nhttps:\/\/doi.org\/10.1159\/000356040<\/p>\n<p>8. Drutel A, Archambeaud F, Caron P. Selenium and the thyroid gland: more good news for clinicians. Clinical Endocrinology. 2013;78(2):155-164. http:\/\/dx.doi.org\/10.1111\/cen.12066<br \/>\nhttps:\/\/doi.org\/10.1111\/cen.12066<\/p>\n<p>9. Shabalina EA, Fadeev VV. Effekty farmakologicheskih doz selena na funkciju shhitovidnoj zhelezy pri autoimmunnom tireoidite. Klinicheskaja i jeksperimental&#8217;naja tireoidologija. 2019;15(2). Russian. Available from:https:\/\/cet-endojournals.ru\/ket\/article\/ view\/10299<\/p>\n<p>10. Caselli E, Zatelli M, Rizzo R, Benedetti S, Martorelli D, Trasforini G, Cassai E, degli Uberti E, Di Luca D, Dolcetti R. Virologic and Immunologic Evidence Supporting an Association between HHV-6 and Hashimoto&#8217;s Thyroiditis. PLoS Pathogens. 2012;8(10):e1002951. http:\/\/dx.doi.org\/10.1371\/journal.ppat.1002951<br \/>\nhttps:\/\/doi.org\/10.1371\/journal.ppat.1002951<\/p>\n<p>11. Eschler D, Hasham A, Tomer Y. Cutting Edge: The Etiology of Autoimmune Thyroid Diseases. Clinical Reviews in Allergy &amp; Immunology. 2011;41(2):190-197. http:\/\/dx.doi.org\/10.1007\/s12016-010-8245-8<br \/>\nhttps:\/\/doi.org\/10.1007\/s12016-010-8245-8<\/p>\n","protected":false},"excerpt":{"rendered":"<p>E.Ya Nikolenko., O.A. Salun, K.V.Vovk, E.L.Pavlova N. Karazin Kharkiv National University, Department of General Practice-Family Medicine This article is about autoimmune thyroid disease, the causes of this pathology, factors of development of AIT. Recent studies have shown that gene mutations, including regulatory genes, cause the development of thyroid, including AIT, so far there is no&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13,10,43,50],"tags":[],"translation":{"provider":"WPGlobus","version":"2.12.2","language":"en","enabled_languages":["uk","en","ru"],"languages":{"uk":{"title":true,"content":true,"excerpt":false},"en":{"title":true,"content":true,"excerpt":false},"ru":{"title":true,"content":true,"excerpt":false}}},"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/1863"}],"collection":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/comments?post=1863"}],"version-history":[{"count":6,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/1863\/revisions"}],"predecessor-version":[{"id":2526,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/posts\/1863\/revisions\/2526"}],"wp:attachment":[{"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/media?parent=1863"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/categories?post=1863"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.internalmed-journal.in.ua\/en\/wp-json\/wp\/v2\/tags?post=1863"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}